{
 "cells": [
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {
    "scrolled": true
   },
   "outputs": [],
   "source": [
    "# @Date:   2019-05-10T13:35:26+08:00\n",
    "# @Email:  1730416009@stu.suda.edu.cn\n",
    "# @Project: M_Rlanguage\n",
    "# @Last modified time: 2019-05-10T13:35:27+08:00\n",
    "\n",
    "\n",
    "# ------------------------------------------------------------------------------\n",
    "## [Description]\n",
    "### This function calculates the fold-change and p-value of two groups.\n",
    "## [Input]\n",
    "### dataframe -> the grouped data; groupVector_a/b --> a vector of groupA that represent the column index;\n",
    "## [Output]\n",
    "### returns the input dataframe with two additional(new) columns: 'fold_change', 'p_value'\n",
    "## [Details]\n",
    "### When calculating the p-value, this function use for-loop to get the results\n",
    "# ------------------------------------------------------------------------------\n",
    "get_Ttest_Result_1 <- function(dfrm, groupVector_a, groupVector_b){\n",
    "    # Get the average value of sample group A (non-smokers) & group B (smokers)\n",
    "    non_smoker_mean <- apply(dfrm[, groupVector_a], 1, mean)\n",
    "    smoker_mean <- apply(dfrm[, groupVector_b], 1, mean)\n",
    "    # Calculate the fold-change\n",
    "    fold_change <- smoker_mean / non_smoker_mean\n",
    "    fold_change_dfrm <- as.data.frame(fold_change)\n",
    "\n",
    "    # Use for-loop to apply t.test and get results of p-value\n",
    "    p_value <- c()\n",
    "    for(i in 1:(dim(dfrm)[1]-1)){ # Ignore the NA value\n",
    "        p_value <- append(p_value, t.test(dfrm[i, groupVector_a], dfrm[i, groupVector_b])$p.value)\n",
    "    }\n",
    "    p_value <- append(p_value, NA) # Handle the NA value\n",
    "    p_value_dfrm <- as.data.frame(p_value)\n",
    "\n",
    "    # Add two new columns to the input dfrm\n",
    "    dfrm <- cbind(dfrm, fold_change_dfrm, p_value_dfrm)\n",
    "    # Return Value\n",
    "    return(dfrm)\n",
    "}\n",
    "\n",
    "\n",
    "# ------------------------------------------------------------------------------\n",
    "## [Description]\n",
    "### This function calculates the fold-change and p-value of two groups.\n",
    "## [Input]\n",
    "### dataframe -> the grouped data; groupVector_a/b --> a vector of groupA that represent the column index;\n",
    "## [Output]\n",
    "### returns the input dataframe with two additional(new) columns: 'fold_change', 'p_value'\n",
    "## [Details]\n",
    "### When calculating the p-value, this function use apply() to get the results\n",
    "## [Notes]\n",
    "### This function is faster than get_Ttest_Result_2()\n",
    "# ------------------------------------------------------------------------------\n",
    "get_Ttest_Result_2 <- function(dfrm, groupVector_a, groupVector_b){\n",
    "    # Get the average value of sample group A (non-smokers) & group B (smokers)\n",
    "    non_smoker_mean <- apply(dfrm[, groupVector_a], 1, mean)\n",
    "    smoker_mean <- apply(dfrm[, groupVector_b], 1, mean)\n",
    "    # Calculate the fold-change\n",
    "    fold_change <- smoker_mean / non_smoker_mean\n",
    "    fold_change_dfrm <- as.data.frame(fold_change)\n",
    "\n",
    "    # Use apply() to apply t.test and get results of p-value\n",
    "    ## Use tempFunction to get p-value\n",
    "    p_value <- apply(dfrm[1:(dim(dfrm)[1]-1),], 1, function(x) t.test(as.numeric(x[groupVector_a]),as.numeric(x[groupVector_b]))$p.value)\n",
    "    p_value <- append(p_value, NA) # Handle the NA value\n",
    "    p_value_dfrm <- as.data.frame(p_value)\n",
    "\n",
    "    # Add two new columns to the input dfrm\n",
    "    dfrm <- cbind(dfrm, fold_change_dfrm, p_value_dfrm)\n",
    "    # Return Value\n",
    "    return(dfrm)\n",
    "}"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [],
   "source": [
    "dfrm <- read.csv('C:\\\\Users\\\\Nature\\\\Desktop\\\\M_RLanguage\\\\Lab_6\\\\GSE5056_series_matrix.txt',\n",
    "                header = TRUE, sep='\\t')\n",
    "# dfrm_1 <- get_Ttest_Result_1(dfrm, 2:19, 20:45)\n",
    "dfrm_2 <- get_Ttest_Result_2(dfrm, 2:19, 20:45)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table>\n",
       "<thead><tr><th></th><th scope=col>ID_REF</th><th scope=col>GSM114034</th><th scope=col>GSM114035</th><th scope=col>GSM114036</th><th scope=col>GSM114037</th><th scope=col>GSM114038</th><th scope=col>GSM114039</th><th scope=col>GSM114040</th><th scope=col>GSM114041</th><th scope=col>GSM114042</th><th scope=col>...</th><th scope=col>GSM114070</th><th scope=col>GSM114071</th><th scope=col>GSM114072</th><th scope=col>GSM114073</th><th scope=col>GSM114074</th><th scope=col>GSM114075</th><th scope=col>GSM114076</th><th scope=col>GSM114077</th><th scope=col>fold_change</th><th scope=col>p_value</th></tr></thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>1</th><td>A28102_at    </td><td> 808.3       </td><td>1390.2       </td><td>  927.4      </td><td> 2360.4      </td><td> 1811.4      </td><td> 1622.7      </td><td>  687.9      </td><td> 1686.7      </td><td>  725.6      </td><td>...          </td><td>  860.1      </td><td> 1516.6      </td><td> 827.6       </td><td> 955.0       </td><td> 731.0       </td><td> 601.8       </td><td>  736.2      </td><td>  534.5      </td><td>1.2205307    </td><td>0.4646315973 </td></tr>\n",
       "\t<tr><th scope=row>2</th><td>AB000114_at  </td><td> 266.2       </td><td> 661.4       </td><td>  231.6      </td><td>   58.9      </td><td>  409.8      </td><td> 1420.4      </td><td>  474.1      </td><td>  313.2      </td><td>  416.7      </td><td>...          </td><td>  401.3      </td><td>  511.3      </td><td> 451.1       </td><td> 266.8       </td><td> 281.6       </td><td> 259.2       </td><td>  237.7      </td><td>  184.4      </td><td>1.6738898    </td><td>0.2057826183 </td></tr>\n",
       "\t<tr><th scope=row>3</th><td>AB000115_at  </td><td>1534.3       </td><td>1657.5       </td><td>  176.2      </td><td> 1472.0      </td><td> 2263.2      </td><td> 1824.5      </td><td> 3256.6      </td><td>  342.2      </td><td>  715.4      </td><td>...          </td><td>  431.4      </td><td> 1188.5      </td><td>1001.8       </td><td> 654.3       </td><td> 915.0       </td><td> 585.0       </td><td>  783.9      </td><td>  981.9      </td><td>1.1665101    </td><td>0.6462842946 </td></tr>\n",
       "\t<tr><th scope=row>4</th><td>AB000220_at  </td><td>6734.1       </td><td>4809.9       </td><td>  566.5      </td><td> 1777.2      </td><td> 1703.8      </td><td> 1873.8      </td><td> 3349.6      </td><td>  506.7      </td><td> 3789.4      </td><td>...          </td><td> 1767.3      </td><td> 3274.8      </td><td>6808.7       </td><td>4181.7       </td><td>4481.5       </td><td>3384.0       </td><td> 3779.8      </td><td> 4480.1      </td><td>1.1164064    </td><td>0.4837524591 </td></tr>\n",
       "\t<tr><th scope=row>5</th><td>AB000381_s_at</td><td> 213.5       </td><td> 119.6       </td><td>  179.2      </td><td>  189.3      </td><td>  301.5      </td><td>  394.2      </td><td>  104.5      </td><td>  164.8      </td><td>  258.0      </td><td>...          </td><td>  214.6      </td><td>   19.7      </td><td> 147.9       </td><td>  36.2       </td><td>  37.2       </td><td> 104.6       </td><td>  164.8      </td><td>  139.3      </td><td>0.7910773    </td><td>0.3202725473 </td></tr>\n",
       "\t<tr><th scope=row>6</th><td>AB000409_at  </td><td>1259.6       </td><td>2000.4       </td><td>  115.9      </td><td>  948.0      </td><td>  443.2      </td><td> 1340.9      </td><td> 2002.3      </td><td>  711.9      </td><td> 1727.9      </td><td>...          </td><td> 1649.8      </td><td> 2041.7      </td><td>2216.3       </td><td>2283.3       </td><td>2462.3       </td><td>2096.5       </td><td> 1881.8      </td><td> 1788.7      </td><td>1.2924453    </td><td>0.1561640071 </td></tr>\n",
       "\t<tr><th scope=row>7</th><td>AB000410_s_at</td><td> 196.2       </td><td> 226.8       </td><td>  416.3      </td><td>  611.0      </td><td>  257.3      </td><td>  457.3      </td><td>  232.0      </td><td>  311.2      </td><td>  254.2      </td><td>...          </td><td>  275.7      </td><td>  178.3      </td><td> 155.9       </td><td> 134.3       </td><td> 143.2       </td><td> 177.0       </td><td>  252.2      </td><td>  246.6      </td><td>0.7104267    </td><td>0.0662604682 </td></tr>\n",
       "\t<tr><th scope=row>8</th><td>AB000449_at  </td><td> 738.9       </td><td> 981.9       </td><td>  747.2      </td><td>  770.7      </td><td>  311.2      </td><td> 1031.8      </td><td>  273.3      </td><td>  568.3      </td><td>  923.5      </td><td>...          </td><td>  680.9      </td><td>  900.6      </td><td>1163.6       </td><td> 600.0       </td><td> 527.4       </td><td> 415.5       </td><td>  404.6      </td><td>  335.1      </td><td>1.4421654    </td><td>0.2666760439 </td></tr>\n",
       "\t<tr><th scope=row>9</th><td>AB000450_at  </td><td>1730.1       </td><td>2172.4       </td><td>  634.9      </td><td>   92.9      </td><td>   93.7      </td><td> 1494.6      </td><td>  318.5      </td><td>  163.4      </td><td> 1148.2      </td><td>...          </td><td> 1345.3      </td><td> 1434.2      </td><td>1388.6       </td><td>1714.9       </td><td>1430.8       </td><td> 946.6       </td><td> 1124.3      </td><td>  758.3      </td><td>1.2933856    </td><td>0.1630920683 </td></tr>\n",
       "\t<tr><th scope=row>10</th><td>AB000460_at  </td><td>3226.0       </td><td>4180.1       </td><td> 2324.8      </td><td> 4784.3      </td><td> 2248.0      </td><td> 2046.0      </td><td> 2212.9      </td><td> 1978.4      </td><td> 4025.7      </td><td>...          </td><td> 3830.3      </td><td> 4688.5      </td><td>4178.1       </td><td>4736.3       </td><td>4023.0       </td><td>3375.1       </td><td> 4664.3      </td><td> 3401.1      </td><td>1.0223681    </td><td>0.7990893435 </td></tr>\n",
       "\t<tr><th scope=row>11</th><td>AB000462_at  </td><td> 561.9       </td><td> 678.7       </td><td>   86.5      </td><td> 1143.4      </td><td>  884.8      </td><td>  613.4      </td><td>  258.3      </td><td>  733.6      </td><td> 1261.0      </td><td>...          </td><td>  877.1      </td><td> 1117.1      </td><td> 648.6       </td><td> 866.5       </td><td> 574.5       </td><td> 513.2       </td><td>  436.3      </td><td>  483.1      </td><td>0.8549584    </td><td>0.4080222344 </td></tr>\n",
       "\t<tr><th scope=row>12</th><td>AB000464_at  </td><td>1789.1       </td><td>1734.0       </td><td>  561.1      </td><td> 1051.8      </td><td>  774.5      </td><td> 1755.2      </td><td>  676.1      </td><td> 1012.5      </td><td> 1920.5      </td><td>...          </td><td> 1297.6      </td><td> 1897.0      </td><td>1075.1       </td><td> 979.9       </td><td> 959.9       </td><td> 781.1       </td><td> 1053.2      </td><td>  837.6      </td><td>0.8838731    </td><td>0.4143224457 </td></tr>\n",
       "\t<tr><th scope=row>13</th><td>AB000466_at  </td><td> 254.8       </td><td> 230.1       </td><td>  265.6      </td><td>  315.6      </td><td>  308.6      </td><td>  239.0      </td><td>   80.1      </td><td>  268.1      </td><td>  213.8      </td><td>...          </td><td>  334.6      </td><td>  275.6      </td><td> 271.8       </td><td> 195.3       </td><td> 216.1       </td><td> 191.3       </td><td>  240.2      </td><td>  159.4      </td><td>1.1589296    </td><td>0.3121915014 </td></tr>\n",
       "\t<tr><th scope=row>14</th><td>AB000467_at  </td><td>1288.8       </td><td> 553.8       </td><td>  584.8      </td><td> 1551.2      </td><td>  454.8      </td><td>  410.9      </td><td>  151.2      </td><td>  240.4      </td><td>  619.2      </td><td>...          </td><td>  310.8      </td><td> 1481.5      </td><td> 446.8       </td><td> 307.1       </td><td> 960.1       </td><td> 780.4       </td><td>  832.5      </td><td>  876.9      </td><td>1.1346905    </td><td>0.6098408798 </td></tr>\n",
       "\t<tr><th scope=row>15</th><td>AB000468_at  </td><td>3932.7       </td><td>4113.8       </td><td> 2913.4      </td><td> 1834.4      </td><td> 2080.5      </td><td> 1781.4      </td><td> 2054.2      </td><td> 1723.9      </td><td> 4117.3      </td><td>...          </td><td> 3038.2      </td><td> 2897.3      </td><td>5860.3       </td><td>4784.3       </td><td>5491.2       </td><td>4909.5       </td><td> 6752.8      </td><td> 3183.8      </td><td>1.2437960    </td><td>0.0310017799 </td></tr>\n",
       "\t<tr><th scope=row>16</th><td>AB000584_at  </td><td>7942.2       </td><td>4851.0       </td><td> 3734.1      </td><td> 1611.0      </td><td> 4057.0      </td><td> 4433.8      </td><td> 4973.0      </td><td> 3974.1      </td><td> 6383.5      </td><td>...          </td><td>13762.8      </td><td> 8570.5      </td><td>5096.6       </td><td>6466.6       </td><td>9896.3       </td><td>8374.3       </td><td> 5511.4      </td><td> 3862.5      </td><td>2.3576472    </td><td>0.0006943714 </td></tr>\n",
       "\t<tr><th scope=row>17</th><td>AB000816_s_at</td><td>  63.4       </td><td> 126.0       </td><td>  116.9      </td><td>  648.8      </td><td>  832.8      </td><td>  507.5      </td><td>   58.5      </td><td>  284.6      </td><td>   61.0      </td><td>...          </td><td>   55.9      </td><td>   94.2      </td><td>  43.6       </td><td>  31.0       </td><td> 343.8       </td><td> 231.1       </td><td>   37.4      </td><td>   34.2      </td><td>0.7053565    </td><td>0.4156251513 </td></tr>\n",
       "\t<tr><th scope=row>18</th><td>AB000895_at  </td><td> 366.9       </td><td> 349.2       </td><td> 1149.2      </td><td> 1196.6      </td><td> 1510.6      </td><td>  720.6      </td><td>  913.0      </td><td>  737.9      </td><td>  302.5      </td><td>...          </td><td>  416.4      </td><td>  361.7      </td><td> 293.4       </td><td> 234.3       </td><td> 300.1       </td><td> 310.0       </td><td>  414.7      </td><td>  341.8      </td><td>1.4204591    </td><td>0.3442482565 </td></tr>\n",
       "\t<tr><th scope=row>19</th><td>AB000896_at  </td><td> 454.7       </td><td>1305.2       </td><td>  562.5      </td><td>  145.4      </td><td>  219.0      </td><td>  981.7      </td><td>   62.9      </td><td>  619.6      </td><td>  806.6      </td><td>...          </td><td>  776.6      </td><td> 1052.5      </td><td>1213.5       </td><td>1508.2       </td><td> 629.4       </td><td> 789.9       </td><td>  844.2      </td><td>  748.2      </td><td>1.1998046    </td><td>0.3262187657 </td></tr>\n",
       "\t<tr><th scope=row>20</th><td>AB000897_at  </td><td> 404.3       </td><td> 558.1       </td><td>  251.3      </td><td>  244.7      </td><td> 1037.2      </td><td> 1218.1      </td><td>   60.6      </td><td>   46.6      </td><td>  333.6      </td><td>...          </td><td>  534.4      </td><td>  983.3      </td><td> 480.4       </td><td> 531.6       </td><td> 469.1       </td><td> 480.3       </td><td>  297.9      </td><td>  337.6      </td><td>1.0579385    </td><td>0.7740405906 </td></tr>\n",
       "\t<tr><th scope=row>21</th><td>AB000905_at  </td><td> 566.5       </td><td>1470.4       </td><td> 1132.1      </td><td>  878.7      </td><td>  817.2      </td><td> 1379.8      </td><td>  368.4      </td><td>  544.6      </td><td>  520.8      </td><td>...          </td><td>  577.5      </td><td>  958.4      </td><td> 510.4       </td><td> 615.6       </td><td> 402.4       </td><td> 339.9       </td><td>  555.4      </td><td>  327.4      </td><td>1.0735278    </td><td>0.6548151800 </td></tr>\n",
       "\t<tr><th scope=row>22</th><td>AB001106_at  </td><td>1530.4       </td><td>1178.6       </td><td>  646.8      </td><td> 1290.6      </td><td> 1550.7      </td><td> 2109.9      </td><td>  595.2      </td><td>  773.0      </td><td> 1238.4      </td><td>...          </td><td>  908.6      </td><td> 1353.3      </td><td>3184.3       </td><td>2289.7       </td><td>1688.3       </td><td>1215.0       </td><td> 1325.8      </td><td> 1335.9      </td><td>1.2692945    </td><td>0.1738027968 </td></tr>\n",
       "\t<tr><th scope=row>23</th><td>AB001325_at  </td><td>6114.8       </td><td>6701.1       </td><td>11676.8      </td><td>12286.2      </td><td>12672.5      </td><td>11541.0      </td><td>11897.8      </td><td>12909.1      </td><td>14098.0      </td><td>...          </td><td>15569.9      </td><td>11471.7      </td><td>8775.9       </td><td>9434.1       </td><td>8223.2       </td><td>9480.4       </td><td>17472.5      </td><td>12793.5      </td><td>1.0653241    </td><td>0.5169829631 </td></tr>\n",
       "\t<tr><th scope=row>24</th><td>AB002314_at  </td><td> 317.3       </td><td> 590.9       </td><td>  823.1      </td><td>  283.0      </td><td> 1986.6      </td><td> 2046.1      </td><td>  963.9      </td><td>  893.8      </td><td>  486.7      </td><td>...          </td><td>  576.9      </td><td>   89.4      </td><td>1119.4       </td><td> 620.6       </td><td> 214.1       </td><td> 259.1       </td><td>  424.3      </td><td>  310.0      </td><td>1.1020200    </td><td>0.7194674566 </td></tr>\n",
       "\t<tr><th scope=row>25</th><td>AB002315_at  </td><td>1654.6       </td><td>2384.4       </td><td> 1077.1      </td><td> 2013.0      </td><td> 1117.1      </td><td> 1226.4      </td><td> 1100.1      </td><td> 1235.1      </td><td> 1617.5      </td><td>...          </td><td> 1237.7      </td><td> 1561.7      </td><td>2047.0       </td><td>2268.5       </td><td>2293.2       </td><td>1715.0       </td><td> 1097.4      </td><td> 1447.1      </td><td>1.0184359    </td><td>0.8386048618 </td></tr>\n",
       "\t<tr><th scope=row>26</th><td>AB002318_at  </td><td>3164.3       </td><td>3521.6       </td><td> 3382.2      </td><td> 5517.7      </td><td> 2271.8      </td><td> 3149.1      </td><td>  339.2      </td><td> 1545.2      </td><td> 1944.0      </td><td>...          </td><td> 2649.4      </td><td> 4960.5      </td><td>2138.6       </td><td>5906.9       </td><td>2616.0       </td><td>2671.8       </td><td> 3894.1      </td><td> 3076.9      </td><td>1.0326219    </td><td>0.7861666325 </td></tr>\n",
       "\t<tr><th scope=row>27</th><td>AB002332_at  </td><td>1732.4       </td><td>1659.3       </td><td>  928.0      </td><td> 1086.1      </td><td> 1210.9      </td><td> 1815.3      </td><td> 1394.1      </td><td>  989.8      </td><td> 1602.7      </td><td>...          </td><td> 2569.6      </td><td> 2991.8      </td><td>4468.7       </td><td>4797.7       </td><td>3222.2       </td><td>2091.1       </td><td> 1889.9      </td><td> 2971.7      </td><td>1.3542307    </td><td>0.0137440249 </td></tr>\n",
       "\t<tr><th scope=row>28</th><td>AB002356_s_at</td><td>2842.2       </td><td>3210.0       </td><td> 5700.3      </td><td> 4649.6      </td><td> 5350.6      </td><td> 4210.5      </td><td> 4373.0      </td><td> 3833.6      </td><td> 4196.9      </td><td>...          </td><td> 3416.1      </td><td> 4840.1      </td><td>2861.1       </td><td>2586.3       </td><td>3531.6       </td><td>3932.3       </td><td> 4509.2      </td><td> 4595.1      </td><td>0.9552646    </td><td>0.4455168414 </td></tr>\n",
       "\t<tr><th scope=row>29</th><td>AB002365_at  </td><td>7780.9       </td><td>5794.6       </td><td>  984.7      </td><td>  770.9      </td><td>  751.4      </td><td>  765.4      </td><td> 1848.7      </td><td> 1452.4      </td><td> 3304.0      </td><td>...          </td><td> 5242.5      </td><td> 4063.0      </td><td>9375.0       </td><td>9765.9       </td><td>8648.1       </td><td>5156.5       </td><td> 3303.9      </td><td> 3450.7      </td><td>1.4099952    </td><td>0.0916796529 </td></tr>\n",
       "\t<tr><th scope=row>30</th><td>AB002366_at  </td><td> 228.8       </td><td> 616.2       </td><td>  628.2      </td><td>  709.0      </td><td>  368.2      </td><td>   60.1      </td><td>   19.5      </td><td>   19.1      </td><td>  304.7      </td><td>...          </td><td>  197.0      </td><td>  136.5      </td><td> 698.1       </td><td> 171.5       </td><td> 261.3       </td><td> 286.8       </td><td>  220.5      </td><td>  232.6      </td><td>0.7162988    </td><td>0.1108929978 </td></tr>\n",
       "\t<tr><th scope=row>...</th><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>   </td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td><td>...</td></tr>\n",
       "\t<tr><th scope=row>7101</th><td>Z80787_at               </td><td>  126.1                 </td><td>  497.5                 </td><td>    77.8                </td><td>  1155.6                </td><td>  576.1                 </td><td>  658.0                 </td><td>  395.0                 </td><td>  595.5                 </td><td>  299.9                 </td><td>...                     </td><td>   66.6                 </td><td>  749.9                 </td><td>  166.6                 </td><td>  238.4                 </td><td>  110.9                 </td><td>   90.9                 </td><td>  219.9                 </td><td>  202.0                 </td><td>0.8234044               </td><td>0.43450344              </td></tr>\n",
       "\t<tr><th scope=row>7102</th><td>Z80788_at               </td><td>   73.9                 </td><td>  558.7                 </td><td>   102.3                </td><td>   157.9                </td><td>  193.7                 </td><td>  540.4                 </td><td>   37.0                 </td><td>  163.8                 </td><td>   42.7                 </td><td>...                     </td><td>   45.2                 </td><td>  251.5                 </td><td>   53.6                 </td><td>   28.3                 </td><td>   35.1                 </td><td>  151.3                 </td><td>  338.2                 </td><td>   54.0                 </td><td>0.8751380               </td><td>0.65234488              </td></tr>\n",
       "\t<tr><th scope=row>7103</th><td>Z81326_at               </td><td>  788.8                 </td><td>  861.4                 </td><td>   179.4                </td><td>   149.9                </td><td>  156.9                 </td><td>  232.7                 </td><td>   78.8                 </td><td>  102.4                 </td><td>  447.5                 </td><td>...                     </td><td>   89.9                 </td><td>   46.8                 </td><td>  324.8                 </td><td>  387.7                 </td><td>  278.7                 </td><td>  274.6                 </td><td>  260.7                 </td><td>   81.8                 </td><td>1.0352864               </td><td>0.87635058              </td></tr>\n",
       "\t<tr><th scope=row>7104</th><td>Z83336_at               </td><td> 2561.8                 </td><td> 4267.8                 </td><td>  2362.6                </td><td>  2982.7                </td><td> 3862.9                 </td><td> 3862.2                 </td><td> 2002.4                 </td><td> 2018.0                 </td><td> 1642.2                 </td><td>...                     </td><td> 2995.4                 </td><td> 3604.4                 </td><td> 2077.6                 </td><td> 2937.8                 </td><td> 1633.8                 </td><td> 1275.1                 </td><td> 2200.8                 </td><td> 2032.8                 </td><td>1.0149418               </td><td>0.90149611              </td></tr>\n",
       "\t<tr><th scope=row>7105</th><td>Z83735_at               </td><td>   42.5                 </td><td>  269.2                 </td><td>   110.2                </td><td>    53.9                </td><td>  407.1                 </td><td>  116.2                 </td><td>   26.1                 </td><td>   14.8                 </td><td>   19.9                 </td><td>...                     </td><td>   24.6                 </td><td>   54.1                 </td><td>   40.3                 </td><td>   16.0                 </td><td>   26.8                 </td><td>   37.9                 </td><td>   32.8                 </td><td>   28.7                 </td><td>0.5469664               </td><td>0.19080285              </td></tr>\n",
       "\t<tr><th scope=row>7106</th><td>Z83741_at               </td><td>  124.0                 </td><td>  131.1                 </td><td>   120.0                </td><td>   179.8                </td><td>  132.8                 </td><td>  173.3                 </td><td>   86.6                 </td><td>  125.5                 </td><td>  386.3                 </td><td>...                     </td><td>  342.9                 </td><td>  406.5                 </td><td>   95.3                 </td><td>   81.0                 </td><td>   66.7                 </td><td>   64.1                 </td><td>  136.8                 </td><td>   90.8                 </td><td>1.0860295               </td><td>0.72942603              </td></tr>\n",
       "\t<tr><th scope=row>7107</th><td>Z83742_at               </td><td>   32.3                 </td><td>  165.7                 </td><td>   349.6                </td><td>    53.9                </td><td>  183.6                 </td><td>  572.5                 </td><td>   43.4                 </td><td>   31.6                 </td><td>   31.1                 </td><td>...                     </td><td>   32.8                 </td><td>   65.5                 </td><td>   42.0                 </td><td>   23.1                 </td><td>   12.1                 </td><td>   23.6                 </td><td>   15.3                 </td><td>   25.4                 </td><td>1.3071643               </td><td>0.54474171              </td></tr>\n",
       "\t<tr><th scope=row>7108</th><td>Z83745_at               </td><td>  369.7                 </td><td>  726.4                 </td><td>  1343.1                </td><td>   816.6                </td><td>   90.7                 </td><td>  159.7                 </td><td>  148.6                 </td><td>   79.3                 </td><td>  243.1                 </td><td>...                     </td><td>  118.9                 </td><td>  114.5                 </td><td>   48.8                 </td><td>   90.4                 </td><td>   55.6                 </td><td>   83.3                 </td><td>   55.1                 </td><td>  240.9                 </td><td>0.5734646               </td><td>0.13331411              </td></tr>\n",
       "\t<tr><th scope=row>7109</th><td>Z83799_at               </td><td>   26.1                 </td><td>   65.6                 </td><td>  1202.5                </td><td>   286.2                </td><td>  303.0                 </td><td>  321.9                 </td><td>   37.3                 </td><td>  162.6                 </td><td>   36.1                 </td><td>...                     </td><td>   48.6                 </td><td>   54.5                 </td><td>   13.2                 </td><td>   17.7                 </td><td>   20.5                 </td><td>   33.7                 </td><td>   35.9                 </td><td>   32.1                 </td><td>0.3939741               </td><td>0.17242262              </td></tr>\n",
       "\t<tr><th scope=row>7110</th><td>Z83800_at               </td><td>  352.3                 </td><td>   19.4                 </td><td>   401.3                </td><td>   576.2                </td><td>  797.7                 </td><td>   64.6                 </td><td>   49.1                 </td><td>   40.7                 </td><td>  236.8                 </td><td>...                     </td><td>   79.0                 </td><td>  143.8                 </td><td>  266.4                 </td><td>   15.0                 </td><td>  340.0                 </td><td>  154.4                 </td><td>  404.1                 </td><td>  294.7                 </td><td>0.7905389               </td><td>0.40226117              </td></tr>\n",
       "\t<tr><th scope=row>7111</th><td>Z83802_at               </td><td>  337.1                 </td><td>  307.2                 </td><td>   485.8                </td><td>   678.4                </td><td> 1076.9                 </td><td>  474.4                 </td><td>   56.9                 </td><td>  434.4                 </td><td>  283.2                 </td><td>...                     </td><td>  582.9                 </td><td>  275.3                 </td><td>  326.8                 </td><td>  111.0                 </td><td>  543.6                 </td><td>  371.6                 </td><td>  588.8                 </td><td>  406.8                 </td><td>0.8005771               </td><td>0.26274790              </td></tr>\n",
       "\t<tr><th scope=row>7112</th><td>Z83803_at               </td><td>   68.5                 </td><td>   85.6                 </td><td>   116.8                </td><td>   201.7                </td><td>  165.7                 </td><td>  154.3                 </td><td>   51.7                 </td><td>  395.7                 </td><td>   68.9                 </td><td>...                     </td><td>   76.4                 </td><td>   80.3                 </td><td>   44.4                 </td><td>   36.0                 </td><td>   41.1                 </td><td>   69.4                 </td><td>   68.1                 </td><td>   92.9                 </td><td>0.6686448               </td><td>0.07976404              </td></tr>\n",
       "\t<tr><th scope=row>7113</th><td>Z83804_at               </td><td>   61.3                 </td><td>   75.2                 </td><td>   729.2                </td><td>   168.2                </td><td>  683.2                 </td><td>  322.0                 </td><td>  237.4                 </td><td>  451.9                 </td><td>   81.3                 </td><td>...                     </td><td>   91.3                 </td><td>  406.4                 </td><td>  148.3                 </td><td>  121.0                 </td><td>   71.9                 </td><td>  110.9                 </td><td>  244.2                 </td><td>  287.2                 </td><td>0.7031139               </td><td>0.20410284              </td></tr>\n",
       "\t<tr><th scope=row>7114</th><td>Z83805_at               </td><td>  179.6                 </td><td>  289.1                 </td><td>   284.0                </td><td>   161.8                </td><td>  145.0                 </td><td>  528.1                 </td><td>  116.4                 </td><td>  211.7                 </td><td>  525.8                 </td><td>...                     </td><td>  943.5                 </td><td>  646.4                 </td><td>  158.0                 </td><td>  119.3                 </td><td>  577.8                 </td><td>  359.5                 </td><td>  893.2                 </td><td>  156.0                 </td><td>1.2699898               </td><td>0.35369954              </td></tr>\n",
       "\t<tr><th scope=row>7115</th><td>Z83806_at               </td><td>   53.5                 </td><td>   40.0                 </td><td>    87.1                </td><td>   313.7                </td><td>  177.0                 </td><td>  849.7                 </td><td>   32.8                 </td><td>  316.1                 </td><td>   52.0                 </td><td>...                     </td><td>  213.8                 </td><td>   90.5                 </td><td>  104.9                 </td><td>    5.4                 </td><td>   16.3                 </td><td>   16.4                 </td><td>   22.5                 </td><td>   35.7                 </td><td>0.4292699               </td><td>0.09874292              </td></tr>\n",
       "\t<tr><th scope=row>7116</th><td>Z83821_cds2_at          </td><td>  146.1                 </td><td>  278.1                 </td><td>  2058.7                </td><td>   249.6                </td><td>  207.8                 </td><td>  394.5                 </td><td>  199.5                 </td><td>  344.1                 </td><td>  307.0                 </td><td>...                     </td><td>  610.4                 </td><td>  382.9                 </td><td> 1118.7                 </td><td> 1178.8                 </td><td>  166.3                 </td><td>  670.9                 </td><td>  252.9                 </td><td>  253.7                 </td><td>0.7882485               </td><td>0.43623384              </td></tr>\n",
       "\t<tr><th scope=row>7117</th><td>Z84483_at               </td><td>  185.9                 </td><td>  256.8                 </td><td>   478.2                </td><td>  2029.4                </td><td>  307.5                 </td><td>  742.8                 </td><td>   63.9                 </td><td>  361.6                 </td><td>  239.0                 </td><td>...                     </td><td>  495.8                 </td><td>  173.2                 </td><td>  148.9                 </td><td>  312.4                 </td><td>  292.7                 </td><td>  410.9                 </td><td>  392.9                 </td><td>  421.4                 </td><td>0.7476435               </td><td>0.29435917              </td></tr>\n",
       "\t<tr><th scope=row>7118</th><td>Z84497_s_at             </td><td> 1125.0                 </td><td>  853.0                 </td><td>  2876.2                </td><td>  3792.7                </td><td> 2349.3                 </td><td> 2008.5                 </td><td> 3001.0                 </td><td> 3842.2                 </td><td> 3214.9                 </td><td>...                     </td><td> 2308.3                 </td><td> 2161.1                 </td><td> 1872.1                 </td><td> 1185.6                 </td><td> 3422.3                 </td><td> 3197.5                 </td><td> 3283.9                 </td><td> 3006.6                 </td><td>0.9001073               </td><td>0.28281687              </td></tr>\n",
       "\t<tr><th scope=row>7119</th><td>Z84718_cds1_at          </td><td> 2431.2                 </td><td> 1020.5                 </td><td>  1098.8                </td><td>   968.2                </td><td> 3332.0                 </td><td> 1502.9                 </td><td> 4954.9                 </td><td>  362.4                 </td><td>  171.6                 </td><td>...                     </td><td> 4677.9                 </td><td> 3882.0                 </td><td> 2561.0                 </td><td> 2550.5                 </td><td> 2872.5                 </td><td> 2619.0                 </td><td>  151.6                 </td><td>  131.0                 </td><td>1.6946233               </td><td>0.02026355              </td></tr>\n",
       "\t<tr><th scope=row>7120</th><td>Z84721_cds1_at          </td><td>  535.7                 </td><td> 1481.3                 </td><td>  1838.9                </td><td>  2931.4                </td><td>  325.4                 </td><td> 1757.0                 </td><td> 2157.3                 </td><td>  403.3                 </td><td>  916.9                 </td><td>...                     </td><td> 2566.6                 </td><td> 1672.5                 </td><td>  312.5                 </td><td> 1611.4                 </td><td>  307.4                 </td><td>  831.7                 </td><td>  933.2                 </td><td> 1145.8                 </td><td>1.0160060               </td><td>0.92983366              </td></tr>\n",
       "\t<tr><th scope=row>7121</th><td>Z84721_cds2_at          </td><td>23432.4                 </td><td>41449.0                 </td><td>159758.0                </td><td>177615.7                </td><td>19759.5                 </td><td>24325.3                 </td><td>23243.7                 </td><td>25641.3                 </td><td>80800.6                 </td><td>...                     </td><td>14150.8                 </td><td>27130.8                 </td><td>85301.5                 </td><td>76879.9                 </td><td>30098.0                 </td><td>27347.9                 </td><td>10624.8                 </td><td>16387.8                 </td><td>0.5790154               </td><td>0.04061564              </td></tr>\n",
       "\t<tr><th scope=row>7122</th><td>Z84722_at               </td><td>  366.7                 </td><td>  420.2                 </td><td>   312.9                </td><td>   522.4                </td><td>  485.6                 </td><td>  262.0                 </td><td>  168.9                 </td><td>  939.8                 </td><td>  379.1                 </td><td>...                     </td><td>  204.8                 </td><td>  457.0                 </td><td>  202.6                 </td><td>  144.5                 </td><td>  182.3                 </td><td>  182.6                 </td><td>  230.8                 </td><td>  235.7                 </td><td>0.8447253               </td><td>0.29572328              </td></tr>\n",
       "\t<tr><th scope=row>7123</th><td>Z86000_at               </td><td> 1202.6                 </td><td> 2693.6                 </td><td>  2538.3                </td><td>  1623.5                </td><td> 2700.2                 </td><td> 2929.6                 </td><td> 1896.8                 </td><td> 1482.5                 </td><td> 1729.3                 </td><td>...                     </td><td> 1419.2                 </td><td> 2507.1                 </td><td> 1372.8                 </td><td> 1759.6                 </td><td> 1282.1                 </td><td> 1636.9                 </td><td> 2858.3                 </td><td> 2130.6                 </td><td>0.9233079               </td><td>0.45124679              </td></tr>\n",
       "\t<tr><th scope=row>7124</th><td>Z93784_at               </td><td> 2439.4                 </td><td> 2272.7                 </td><td>  3203.0                </td><td>  2803.5                </td><td> 4800.7                 </td><td> 2997.4                 </td><td> 2089.7                 </td><td> 2251.9                 </td><td> 3487.3                 </td><td>...                     </td><td> 2748.0                 </td><td> 1570.0                 </td><td> 2403.3                 </td><td> 2482.0                 </td><td> 3044.4                 </td><td> 2692.3                 </td><td> 3655.4                 </td><td> 2798.9                 </td><td>0.8241107               </td><td>0.02385007              </td></tr>\n",
       "\t<tr><th scope=row>7125</th><td>Z94753_s_at             </td><td>  429.7                 </td><td>  911.7                 </td><td>  1171.2                </td><td>   516.1                </td><td>  737.9                 </td><td> 1157.7                 </td><td>  211.6                 </td><td>  522.2                 </td><td>  309.9                 </td><td>...                     </td><td>  365.9                 </td><td> 1413.1                 </td><td>  558.3                 </td><td>  227.6                 </td><td>  775.7                 </td><td>  997.8                 </td><td>  331.3                 </td><td>  376.4                 </td><td>1.1540683               </td><td>0.42713655              </td></tr>\n",
       "\t<tr><th scope=row>7126</th><td>Z95624_at               </td><td>  351.9                 </td><td>  105.7                 </td><td>   946.4                </td><td>   389.3                </td><td>  238.1                 </td><td> 1216.7                 </td><td>  227.3                 </td><td>  207.1                 </td><td>  244.2                 </td><td>...                     </td><td>  313.5                 </td><td>  300.7                 </td><td>  120.1                 </td><td>  293.7                 </td><td>  289.1                 </td><td>  291.6                 </td><td>  359.7                 </td><td>  367.3                 </td><td>0.9463065               </td><td>0.79422427              </td></tr>\n",
       "\t<tr><th scope=row>7127</th><td>Z96810_at               </td><td>  411.1                 </td><td>  532.0                 </td><td>  1382.2                </td><td>   242.2                </td><td>  247.2                 </td><td>  940.0                 </td><td>  458.3                 </td><td>  689.7                 </td><td>  760.6                 </td><td>...                     </td><td>  515.5                 </td><td>  925.0                 </td><td>  380.7                 </td><td>  252.1                 </td><td>  443.5                 </td><td>  512.0                 </td><td>  753.9                 </td><td>  741.6                 </td><td>0.7585332               </td><td>0.06665884              </td></tr>\n",
       "\t<tr><th scope=row>7128</th><td>Z97054_xpt2_at          </td><td> 1598.2                 </td><td> 1059.8                 </td><td>  2133.0                </td><td>  2847.0                </td><td> 1369.1                 </td><td> 1783.8                 </td><td> 2786.8                 </td><td> 2616.4                 </td><td> 3217.6                 </td><td>...                     </td><td> 2294.0                 </td><td> 2282.3                 </td><td> 2347.0                 </td><td> 2032.5                 </td><td> 3736.4                 </td><td> 3044.0                 </td><td> 2681.7                 </td><td> 3285.7                 </td><td>1.0767952               </td><td>0.35905502              </td></tr>\n",
       "\t<tr><th scope=row>7129</th><td>Z97074_at               </td><td> 1277.9                 </td><td> 1370.1                 </td><td>  2514.6                </td><td>   277.4                </td><td> 2461.0                 </td><td> 1248.9                 </td><td> 1726.4                 </td><td> 1260.2                 </td><td> 1085.5                 </td><td>...                     </td><td> 1475.8                 </td><td>  737.4                 </td><td> 1614.7                 </td><td> 1421.4                 </td><td> 1238.9                 </td><td> 1719.9                 </td><td>  936.3                 </td><td> 1254.6                 </td><td>0.9389230               </td><td>0.57004284              </td></tr>\n",
       "\t<tr><th scope=row></th><td>!series_matrix_table_end</td><td>     NA                 </td><td>     NA                 </td><td>      NA                </td><td>      NA                </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>...                     </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>     NA                 </td><td>       NA               </td><td>        NA              </td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "\\begin{tabular}{r|lllllllllllllllllllllllllllllllllllllllllllllll}\n",
       "  & ID\\_REF & GSM114034 & GSM114035 & GSM114036 & GSM114037 & GSM114038 & GSM114039 & GSM114040 & GSM114041 & GSM114042 & ... & GSM114070 & GSM114071 & GSM114072 & GSM114073 & GSM114074 & GSM114075 & GSM114076 & GSM114077 & fold\\_change & p\\_value\\\\\n",
       "\\hline\n",
       "\t1 & A28102\\_at     &  808.3          & 1390.2          &   927.4         &  2360.4         &  1811.4         &  1622.7         &   687.9         &  1686.7         &   725.6         & ...             &   860.1         &  1516.6         &  827.6          &  955.0          &  731.0          &  601.8          &   736.2         &   534.5         & 1.2205307       & 0.4646315973   \\\\\n",
       "\t2 & AB000114\\_at   &  266.2          &  661.4          &   231.6         &    58.9         &   409.8         &  1420.4         &   474.1         &   313.2         &   416.7         & ...             &   401.3         &   511.3         &  451.1          &  266.8          &  281.6          &  259.2          &   237.7         &   184.4         & 1.6738898       & 0.2057826183   \\\\\n",
       "\t3 & AB000115\\_at   & 1534.3          & 1657.5          &   176.2         &  1472.0         &  2263.2         &  1824.5         &  3256.6         &   342.2         &   715.4         & ...             &   431.4         &  1188.5         & 1001.8          &  654.3          &  915.0          &  585.0          &   783.9         &   981.9         & 1.1665101       & 0.6462842946   \\\\\n",
       "\t4 & AB000220\\_at   & 6734.1          & 4809.9          &   566.5         &  1777.2         &  1703.8         &  1873.8         &  3349.6         &   506.7         &  3789.4         & ...             &  1767.3         &  3274.8         & 6808.7          & 4181.7          & 4481.5          & 3384.0          &  3779.8         &  4480.1         & 1.1164064       & 0.4837524591   \\\\\n",
       "\t5 & AB000381\\_s\\_at &  213.5            &  119.6            &   179.2           &   189.3           &   301.5           &   394.2           &   104.5           &   164.8           &   258.0           & ...               &   214.6           &    19.7           &  147.9            &   36.2            &   37.2            &  104.6            &   164.8           &   139.3           & 0.7910773         & 0.3202725473     \\\\\n",
       "\t6 & AB000409\\_at   & 1259.6          & 2000.4          &   115.9         &   948.0         &   443.2         &  1340.9         &  2002.3         &   711.9         &  1727.9         & ...             &  1649.8         &  2041.7         & 2216.3          & 2283.3          & 2462.3          & 2096.5          &  1881.8         &  1788.7         & 1.2924453       & 0.1561640071   \\\\\n",
       "\t7 & AB000410\\_s\\_at &  196.2            &  226.8            &   416.3           &   611.0           &   257.3           &   457.3           &   232.0           &   311.2           &   254.2           & ...               &   275.7           &   178.3           &  155.9            &  134.3            &  143.2            &  177.0            &   252.2           &   246.6           & 0.7104267         & 0.0662604682     \\\\\n",
       "\t8 & AB000449\\_at   &  738.9          &  981.9          &   747.2         &   770.7         &   311.2         &  1031.8         &   273.3         &   568.3         &   923.5         & ...             &   680.9         &   900.6         & 1163.6          &  600.0          &  527.4          &  415.5          &   404.6         &   335.1         & 1.4421654       & 0.2666760439   \\\\\n",
       "\t9 & AB000450\\_at   & 1730.1          & 2172.4          &   634.9         &    92.9         &    93.7         &  1494.6         &   318.5         &   163.4         &  1148.2         & ...             &  1345.3         &  1434.2         & 1388.6          & 1714.9          & 1430.8          &  946.6          &  1124.3         &   758.3         & 1.2933856       & 0.1630920683   \\\\\n",
       "\t10 & AB000460\\_at   & 3226.0          & 4180.1          &  2324.8         &  4784.3         &  2248.0         &  2046.0         &  2212.9         &  1978.4         &  4025.7         & ...             &  3830.3         &  4688.5         & 4178.1          & 4736.3          & 4023.0          & 3375.1          &  4664.3         &  3401.1         & 1.0223681       & 0.7990893435   \\\\\n",
       "\t11 & AB000462\\_at   &  561.9          &  678.7          &    86.5         &  1143.4         &   884.8         &   613.4         &   258.3         &   733.6         &  1261.0         & ...             &   877.1         &  1117.1         &  648.6          &  866.5          &  574.5          &  513.2          &   436.3         &   483.1         & 0.8549584       & 0.4080222344   \\\\\n",
       "\t12 & AB000464\\_at   & 1789.1          & 1734.0          &   561.1         &  1051.8         &   774.5         &  1755.2         &   676.1         &  1012.5         &  1920.5         & ...             &  1297.6         &  1897.0         & 1075.1          &  979.9          &  959.9          &  781.1          &  1053.2         &   837.6         & 0.8838731       & 0.4143224457   \\\\\n",
       "\t13 & AB000466\\_at   &  254.8          &  230.1          &   265.6         &   315.6         &   308.6         &   239.0         &    80.1         &   268.1         &   213.8         & ...             &   334.6         &   275.6         &  271.8          &  195.3          &  216.1          &  191.3          &   240.2         &   159.4         & 1.1589296       & 0.3121915014   \\\\\n",
       "\t14 & AB000467\\_at   & 1288.8          &  553.8          &   584.8         &  1551.2         &   454.8         &   410.9         &   151.2         &   240.4         &   619.2         & ...             &   310.8         &  1481.5         &  446.8          &  307.1          &  960.1          &  780.4          &   832.5         &   876.9         & 1.1346905       & 0.6098408798   \\\\\n",
       "\t15 & AB000468\\_at   & 3932.7          & 4113.8          &  2913.4         &  1834.4         &  2080.5         &  1781.4         &  2054.2         &  1723.9         &  4117.3         & ...             &  3038.2         &  2897.3         & 5860.3          & 4784.3          & 5491.2          & 4909.5          &  6752.8         &  3183.8         & 1.2437960       & 0.0310017799   \\\\\n",
       "\t16 & AB000584\\_at   & 7942.2          & 4851.0          &  3734.1         &  1611.0         &  4057.0         &  4433.8         &  4973.0         &  3974.1         &  6383.5         & ...             & 13762.8         &  8570.5         & 5096.6          & 6466.6          & 9896.3          & 8374.3          &  5511.4         &  3862.5         & 2.3576472       & 0.0006943714   \\\\\n",
       "\t17 & AB000816\\_s\\_at &   63.4            &  126.0            &   116.9           &   648.8           &   832.8           &   507.5           &    58.5           &   284.6           &    61.0           & ...               &    55.9           &    94.2           &   43.6            &   31.0            &  343.8            &  231.1            &    37.4           &    34.2           & 0.7053565         & 0.4156251513     \\\\\n",
       "\t18 & AB000895\\_at   &  366.9          &  349.2          &  1149.2         &  1196.6         &  1510.6         &   720.6         &   913.0         &   737.9         &   302.5         & ...             &   416.4         &   361.7         &  293.4          &  234.3          &  300.1          &  310.0          &   414.7         &   341.8         & 1.4204591       & 0.3442482565   \\\\\n",
       "\t19 & AB000896\\_at   &  454.7          & 1305.2          &   562.5         &   145.4         &   219.0         &   981.7         &    62.9         &   619.6         &   806.6         & ...             &   776.6         &  1052.5         & 1213.5          & 1508.2          &  629.4          &  789.9          &   844.2         &   748.2         & 1.1998046       & 0.3262187657   \\\\\n",
       "\t20 & AB000897\\_at   &  404.3          &  558.1          &   251.3         &   244.7         &  1037.2         &  1218.1         &    60.6         &    46.6         &   333.6         & ...             &   534.4         &   983.3         &  480.4          &  531.6          &  469.1          &  480.3          &   297.9         &   337.6         & 1.0579385       & 0.7740405906   \\\\\n",
       "\t21 & AB000905\\_at   &  566.5          & 1470.4          &  1132.1         &   878.7         &   817.2         &  1379.8         &   368.4         &   544.6         &   520.8         & ...             &   577.5         &   958.4         &  510.4          &  615.6          &  402.4          &  339.9          &   555.4         &   327.4         & 1.0735278       & 0.6548151800   \\\\\n",
       "\t22 & AB001106\\_at   & 1530.4          & 1178.6          &   646.8         &  1290.6         &  1550.7         &  2109.9         &   595.2         &   773.0         &  1238.4         & ...             &   908.6         &  1353.3         & 3184.3          & 2289.7          & 1688.3          & 1215.0          &  1325.8         &  1335.9         & 1.2692945       & 0.1738027968   \\\\\n",
       "\t23 & AB001325\\_at   & 6114.8          & 6701.1          & 11676.8         & 12286.2         & 12672.5         & 11541.0         & 11897.8         & 12909.1         & 14098.0         & ...             & 15569.9         & 11471.7         & 8775.9          & 9434.1          & 8223.2          & 9480.4          & 17472.5         & 12793.5         & 1.0653241       & 0.5169829631   \\\\\n",
       "\t24 & AB002314\\_at   &  317.3          &  590.9          &   823.1         &   283.0         &  1986.6         &  2046.1         &   963.9         &   893.8         &   486.7         & ...             &   576.9         &    89.4         & 1119.4          &  620.6          &  214.1          &  259.1          &   424.3         &   310.0         & 1.1020200       & 0.7194674566   \\\\\n",
       "\t25 & AB002315\\_at   & 1654.6          & 2384.4          &  1077.1         &  2013.0         &  1117.1         &  1226.4         &  1100.1         &  1235.1         &  1617.5         & ...             &  1237.7         &  1561.7         & 2047.0          & 2268.5          & 2293.2          & 1715.0          &  1097.4         &  1447.1         & 1.0184359       & 0.8386048618   \\\\\n",
       "\t26 & AB002318\\_at   & 3164.3          & 3521.6          &  3382.2         &  5517.7         &  2271.8         &  3149.1         &   339.2         &  1545.2         &  1944.0         & ...             &  2649.4         &  4960.5         & 2138.6          & 5906.9          & 2616.0          & 2671.8          &  3894.1         &  3076.9         & 1.0326219       & 0.7861666325   \\\\\n",
       "\t27 & AB002332\\_at   & 1732.4          & 1659.3          &   928.0         &  1086.1         &  1210.9         &  1815.3         &  1394.1         &   989.8         &  1602.7         & ...             &  2569.6         &  2991.8         & 4468.7          & 4797.7          & 3222.2          & 2091.1          &  1889.9         &  2971.7         & 1.3542307       & 0.0137440249   \\\\\n",
       "\t28 & AB002356\\_s\\_at & 2842.2            & 3210.0            &  5700.3           &  4649.6           &  5350.6           &  4210.5           &  4373.0           &  3833.6           &  4196.9           & ...               &  3416.1           &  4840.1           & 2861.1            & 2586.3            & 3531.6            & 3932.3            &  4509.2           &  4595.1           & 0.9552646         & 0.4455168414     \\\\\n",
       "\t29 & AB002365\\_at   & 7780.9          & 5794.6          &   984.7         &   770.9         &   751.4         &   765.4         &  1848.7         &  1452.4         &  3304.0         & ...             &  5242.5         &  4063.0         & 9375.0          & 9765.9          & 8648.1          & 5156.5          &  3303.9         &  3450.7         & 1.4099952       & 0.0916796529   \\\\\n",
       "\t30 & AB002366\\_at   &  228.8          &  616.2          &   628.2         &   709.0         &   368.2         &    60.1         &    19.5         &    19.1         &   304.7         & ...             &   197.0         &   136.5         &  698.1          &  171.5          &  261.3          &  286.8          &   220.5         &   232.6         & 0.7162988       & 0.1108929978   \\\\\n",
       "\t... & ... & ... & ... & ... & ... & ... & ... & ... & ... & ... &     & ... & ... & ... & ... & ... & ... & ... & ... & ... & ...\\\\\n",
       "\t7101 & Z80787\\_at                &   126.1                    &   497.5                    &     77.8                   &   1155.6                   &   576.1                    &   658.0                    &   395.0                    &   595.5                    &   299.9                    & ...                        &    66.6                    &   749.9                    &   166.6                    &   238.4                    &   110.9                    &    90.9                    &   219.9                    &   202.0                    & 0.8234044                  & 0.43450344                \\\\\n",
       "\t7102 & Z80788\\_at                &    73.9                    &   558.7                    &    102.3                   &    157.9                   &   193.7                    &   540.4                    &    37.0                    &   163.8                    &    42.7                    & ...                        &    45.2                    &   251.5                    &    53.6                    &    28.3                    &    35.1                    &   151.3                    &   338.2                    &    54.0                    & 0.8751380                  & 0.65234488                \\\\\n",
       "\t7103 & Z81326\\_at                &   788.8                    &   861.4                    &    179.4                   &    149.9                   &   156.9                    &   232.7                    &    78.8                    &   102.4                    &   447.5                    & ...                        &    89.9                    &    46.8                    &   324.8                    &   387.7                    &   278.7                    &   274.6                    &   260.7                    &    81.8                    & 1.0352864                  & 0.87635058                \\\\\n",
       "\t7104 & Z83336\\_at                &  2561.8                    &  4267.8                    &   2362.6                   &   2982.7                   &  3862.9                    &  3862.2                    &  2002.4                    &  2018.0                    &  1642.2                    & ...                        &  2995.4                    &  3604.4                    &  2077.6                    &  2937.8                    &  1633.8                    &  1275.1                    &  2200.8                    &  2032.8                    & 1.0149418                  & 0.90149611                \\\\\n",
       "\t7105 & Z83735\\_at                &    42.5                    &   269.2                    &    110.2                   &     53.9                   &   407.1                    &   116.2                    &    26.1                    &    14.8                    &    19.9                    & ...                        &    24.6                    &    54.1                    &    40.3                    &    16.0                    &    26.8                    &    37.9                    &    32.8                    &    28.7                    & 0.5469664                  & 0.19080285                \\\\\n",
       "\t7106 & Z83741\\_at                &   124.0                    &   131.1                    &    120.0                   &    179.8                   &   132.8                    &   173.3                    &    86.6                    &   125.5                    &   386.3                    & ...                        &   342.9                    &   406.5                    &    95.3                    &    81.0                    &    66.7                    &    64.1                    &   136.8                    &    90.8                    & 1.0860295                  & 0.72942603                \\\\\n",
       "\t7107 & Z83742\\_at                &    32.3                    &   165.7                    &    349.6                   &     53.9                   &   183.6                    &   572.5                    &    43.4                    &    31.6                    &    31.1                    & ...                        &    32.8                    &    65.5                    &    42.0                    &    23.1                    &    12.1                    &    23.6                    &    15.3                    &    25.4                    & 1.3071643                  & 0.54474171                \\\\\n",
       "\t7108 & Z83745\\_at                &   369.7                    &   726.4                    &   1343.1                   &    816.6                   &    90.7                    &   159.7                    &   148.6                    &    79.3                    &   243.1                    & ...                        &   118.9                    &   114.5                    &    48.8                    &    90.4                    &    55.6                    &    83.3                    &    55.1                    &   240.9                    & 0.5734646                  & 0.13331411                \\\\\n",
       "\t7109 & Z83799\\_at                &    26.1                    &    65.6                    &   1202.5                   &    286.2                   &   303.0                    &   321.9                    &    37.3                    &   162.6                    &    36.1                    & ...                        &    48.6                    &    54.5                    &    13.2                    &    17.7                    &    20.5                    &    33.7                    &    35.9                    &    32.1                    & 0.3939741                  & 0.17242262                \\\\\n",
       "\t7110 & Z83800\\_at                &   352.3                    &    19.4                    &    401.3                   &    576.2                   &   797.7                    &    64.6                    &    49.1                    &    40.7                    &   236.8                    & ...                        &    79.0                    &   143.8                    &   266.4                    &    15.0                    &   340.0                    &   154.4                    &   404.1                    &   294.7                    & 0.7905389                  & 0.40226117                \\\\\n",
       "\t7111 & Z83802\\_at                &   337.1                    &   307.2                    &    485.8                   &    678.4                   &  1076.9                    &   474.4                    &    56.9                    &   434.4                    &   283.2                    & ...                        &   582.9                    &   275.3                    &   326.8                    &   111.0                    &   543.6                    &   371.6                    &   588.8                    &   406.8                    & 0.8005771                  & 0.26274790                \\\\\n",
       "\t7112 & Z83803\\_at                &    68.5                    &    85.6                    &    116.8                   &    201.7                   &   165.7                    &   154.3                    &    51.7                    &   395.7                    &    68.9                    & ...                        &    76.4                    &    80.3                    &    44.4                    &    36.0                    &    41.1                    &    69.4                    &    68.1                    &    92.9                    & 0.6686448                  & 0.07976404                \\\\\n",
       "\t7113 & Z83804\\_at                &    61.3                    &    75.2                    &    729.2                   &    168.2                   &   683.2                    &   322.0                    &   237.4                    &   451.9                    &    81.3                    & ...                        &    91.3                    &   406.4                    &   148.3                    &   121.0                    &    71.9                    &   110.9                    &   244.2                    &   287.2                    & 0.7031139                  & 0.20410284                \\\\\n",
       "\t7114 & Z83805\\_at                &   179.6                    &   289.1                    &    284.0                   &    161.8                   &   145.0                    &   528.1                    &   116.4                    &   211.7                    &   525.8                    & ...                        &   943.5                    &   646.4                    &   158.0                    &   119.3                    &   577.8                    &   359.5                    &   893.2                    &   156.0                    & 1.2699898                  & 0.35369954                \\\\\n",
       "\t7115 & Z83806\\_at                &    53.5                    &    40.0                    &     87.1                   &    313.7                   &   177.0                    &   849.7                    &    32.8                    &   316.1                    &    52.0                    & ...                        &   213.8                    &    90.5                    &   104.9                    &     5.4                    &    16.3                    &    16.4                    &    22.5                    &    35.7                    & 0.4292699                  & 0.09874292                \\\\\n",
       "\t7116 & Z83821\\_cds2\\_at           &   146.1                      &   278.1                      &   2058.7                     &    249.6                     &   207.8                      &   394.5                      &   199.5                      &   344.1                      &   307.0                      & ...                          &   610.4                      &   382.9                      &  1118.7                      &  1178.8                      &   166.3                      &   670.9                      &   252.9                      &   253.7                      & 0.7882485                    & 0.43623384                  \\\\\n",
       "\t7117 & Z84483\\_at                &   185.9                    &   256.8                    &    478.2                   &   2029.4                   &   307.5                    &   742.8                    &    63.9                    &   361.6                    &   239.0                    & ...                        &   495.8                    &   173.2                    &   148.9                    &   312.4                    &   292.7                    &   410.9                    &   392.9                    &   421.4                    & 0.7476435                  & 0.29435917                \\\\\n",
       "\t7118 & Z84497\\_s\\_at              &  1125.0                      &   853.0                      &   2876.2                     &   3792.7                     &  2349.3                      &  2008.5                      &  3001.0                      &  3842.2                      &  3214.9                      & ...                          &  2308.3                      &  2161.1                      &  1872.1                      &  1185.6                      &  3422.3                      &  3197.5                      &  3283.9                      &  3006.6                      & 0.9001073                    & 0.28281687                  \\\\\n",
       "\t7119 & Z84718\\_cds1\\_at           &  2431.2                      &  1020.5                      &   1098.8                     &    968.2                     &  3332.0                      &  1502.9                      &  4954.9                      &   362.4                      &   171.6                      & ...                          &  4677.9                      &  3882.0                      &  2561.0                      &  2550.5                      &  2872.5                      &  2619.0                      &   151.6                      &   131.0                      & 1.6946233                    & 0.02026355                  \\\\\n",
       "\t7120 & Z84721\\_cds1\\_at           &   535.7                      &  1481.3                      &   1838.9                     &   2931.4                     &   325.4                      &  1757.0                      &  2157.3                      &   403.3                      &   916.9                      & ...                          &  2566.6                      &  1672.5                      &   312.5                      &  1611.4                      &   307.4                      &   831.7                      &   933.2                      &  1145.8                      & 1.0160060                    & 0.92983366                  \\\\\n",
       "\t7121 & Z84721\\_cds2\\_at           & 23432.4                      & 41449.0                      & 159758.0                     & 177615.7                     & 19759.5                      & 24325.3                      & 23243.7                      & 25641.3                      & 80800.6                      & ...                          & 14150.8                      & 27130.8                      & 85301.5                      & 76879.9                      & 30098.0                      & 27347.9                      & 10624.8                      & 16387.8                      & 0.5790154                    & 0.04061564                  \\\\\n",
       "\t7122 & Z84722\\_at                &   366.7                    &   420.2                    &    312.9                   &    522.4                   &   485.6                    &   262.0                    &   168.9                    &   939.8                    &   379.1                    & ...                        &   204.8                    &   457.0                    &   202.6                    &   144.5                    &   182.3                    &   182.6                    &   230.8                    &   235.7                    & 0.8447253                  & 0.29572328                \\\\\n",
       "\t7123 & Z86000\\_at                &  1202.6                    &  2693.6                    &   2538.3                   &   1623.5                   &  2700.2                    &  2929.6                    &  1896.8                    &  1482.5                    &  1729.3                    & ...                        &  1419.2                    &  2507.1                    &  1372.8                    &  1759.6                    &  1282.1                    &  1636.9                    &  2858.3                    &  2130.6                    & 0.9233079                  & 0.45124679                \\\\\n",
       "\t7124 & Z93784\\_at                &  2439.4                    &  2272.7                    &   3203.0                   &   2803.5                   &  4800.7                    &  2997.4                    &  2089.7                    &  2251.9                    &  3487.3                    & ...                        &  2748.0                    &  1570.0                    &  2403.3                    &  2482.0                    &  3044.4                    &  2692.3                    &  3655.4                    &  2798.9                    & 0.8241107                  & 0.02385007                \\\\\n",
       "\t7125 & Z94753\\_s\\_at              &   429.7                      &   911.7                      &   1171.2                     &    516.1                     &   737.9                      &  1157.7                      &   211.6                      &   522.2                      &   309.9                      & ...                          &   365.9                      &  1413.1                      &   558.3                      &   227.6                      &   775.7                      &   997.8                      &   331.3                      &   376.4                      & 1.1540683                    & 0.42713655                  \\\\\n",
       "\t7126 & Z95624\\_at                &   351.9                    &   105.7                    &    946.4                   &    389.3                   &   238.1                    &  1216.7                    &   227.3                    &   207.1                    &   244.2                    & ...                        &   313.5                    &   300.7                    &   120.1                    &   293.7                    &   289.1                    &   291.6                    &   359.7                    &   367.3                    & 0.9463065                  & 0.79422427                \\\\\n",
       "\t7127 & Z96810\\_at                &   411.1                    &   532.0                    &   1382.2                   &    242.2                   &   247.2                    &   940.0                    &   458.3                    &   689.7                    &   760.6                    & ...                        &   515.5                    &   925.0                    &   380.7                    &   252.1                    &   443.5                    &   512.0                    &   753.9                    &   741.6                    & 0.7585332                  & 0.06665884                \\\\\n",
       "\t7128 & Z97054\\_xpt2\\_at           &  1598.2                      &  1059.8                      &   2133.0                     &   2847.0                     &  1369.1                      &  1783.8                      &  2786.8                      &  2616.4                      &  3217.6                      & ...                          &  2294.0                      &  2282.3                      &  2347.0                      &  2032.5                      &  3736.4                      &  3044.0                      &  2681.7                      &  3285.7                      & 1.0767952                    & 0.35905502                  \\\\\n",
       "\t7129 & Z97074\\_at                &  1277.9                    &  1370.1                    &   2514.6                   &    277.4                   &  2461.0                    &  1248.9                    &  1726.4                    &  1260.2                    &  1085.5                    & ...                        &  1475.8                    &   737.4                    &  1614.7                    &  1421.4                    &  1238.9                    &  1719.9                    &   936.3                    &  1254.6                    & 0.9389230                  & 0.57004284                \\\\\n",
       "\t & !series\\_matrix\\_table\\_end &      NA                        &      NA                        &       NA                       &       NA                       &      NA                        &      NA                        &      NA                        &      NA                        &      NA                        & ...                            &      NA                        &      NA                        &      NA                        &      NA                        &      NA                        &      NA                        &      NA                        &      NA                        &        NA                      &         NA                    \\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "| <!--/--> | ID_REF | GSM114034 | GSM114035 | GSM114036 | GSM114037 | GSM114038 | GSM114039 | GSM114040 | GSM114041 | GSM114042 | ... | GSM114070 | GSM114071 | GSM114072 | GSM114073 | GSM114074 | GSM114075 | GSM114076 | GSM114077 | fold_change | p_value |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| 1 | A28102_at     |  808.3        | 1390.2        |   927.4       |  2360.4       |  1811.4       |  1622.7       |   687.9       |  1686.7       |   725.6       | ...           |   860.1       |  1516.6       |  827.6        |  955.0        |  731.0        |  601.8        |   736.2       |   534.5       | 1.2205307     | 0.4646315973  |\n",
       "| 2 | AB000114_at   |  266.2        |  661.4        |   231.6       |    58.9       |   409.8       |  1420.4       |   474.1       |   313.2       |   416.7       | ...           |   401.3       |   511.3       |  451.1        |  266.8        |  281.6        |  259.2        |   237.7       |   184.4       | 1.6738898     | 0.2057826183  |\n",
       "| 3 | AB000115_at   | 1534.3        | 1657.5        |   176.2       |  1472.0       |  2263.2       |  1824.5       |  3256.6       |   342.2       |   715.4       | ...           |   431.4       |  1188.5       | 1001.8        |  654.3        |  915.0        |  585.0        |   783.9       |   981.9       | 1.1665101     | 0.6462842946  |\n",
       "| 4 | AB000220_at   | 6734.1        | 4809.9        |   566.5       |  1777.2       |  1703.8       |  1873.8       |  3349.6       |   506.7       |  3789.4       | ...           |  1767.3       |  3274.8       | 6808.7        | 4181.7        | 4481.5        | 3384.0        |  3779.8       |  4480.1       | 1.1164064     | 0.4837524591  |\n",
       "| 5 | AB000381_s_at |  213.5        |  119.6        |   179.2       |   189.3       |   301.5       |   394.2       |   104.5       |   164.8       |   258.0       | ...           |   214.6       |    19.7       |  147.9        |   36.2        |   37.2        |  104.6        |   164.8       |   139.3       | 0.7910773     | 0.3202725473  |\n",
       "| 6 | AB000409_at   | 1259.6        | 2000.4        |   115.9       |   948.0       |   443.2       |  1340.9       |  2002.3       |   711.9       |  1727.9       | ...           |  1649.8       |  2041.7       | 2216.3        | 2283.3        | 2462.3        | 2096.5        |  1881.8       |  1788.7       | 1.2924453     | 0.1561640071  |\n",
       "| 7 | AB000410_s_at |  196.2        |  226.8        |   416.3       |   611.0       |   257.3       |   457.3       |   232.0       |   311.2       |   254.2       | ...           |   275.7       |   178.3       |  155.9        |  134.3        |  143.2        |  177.0        |   252.2       |   246.6       | 0.7104267     | 0.0662604682  |\n",
       "| 8 | AB000449_at   |  738.9        |  981.9        |   747.2       |   770.7       |   311.2       |  1031.8       |   273.3       |   568.3       |   923.5       | ...           |   680.9       |   900.6       | 1163.6        |  600.0        |  527.4        |  415.5        |   404.6       |   335.1       | 1.4421654     | 0.2666760439  |\n",
       "| 9 | AB000450_at   | 1730.1        | 2172.4        |   634.9       |    92.9       |    93.7       |  1494.6       |   318.5       |   163.4       |  1148.2       | ...           |  1345.3       |  1434.2       | 1388.6        | 1714.9        | 1430.8        |  946.6        |  1124.3       |   758.3       | 1.2933856     | 0.1630920683  |\n",
       "| 10 | AB000460_at   | 3226.0        | 4180.1        |  2324.8       |  4784.3       |  2248.0       |  2046.0       |  2212.9       |  1978.4       |  4025.7       | ...           |  3830.3       |  4688.5       | 4178.1        | 4736.3        | 4023.0        | 3375.1        |  4664.3       |  3401.1       | 1.0223681     | 0.7990893435  |\n",
       "| 11 | AB000462_at   |  561.9        |  678.7        |    86.5       |  1143.4       |   884.8       |   613.4       |   258.3       |   733.6       |  1261.0       | ...           |   877.1       |  1117.1       |  648.6        |  866.5        |  574.5        |  513.2        |   436.3       |   483.1       | 0.8549584     | 0.4080222344  |\n",
       "| 12 | AB000464_at   | 1789.1        | 1734.0        |   561.1       |  1051.8       |   774.5       |  1755.2       |   676.1       |  1012.5       |  1920.5       | ...           |  1297.6       |  1897.0       | 1075.1        |  979.9        |  959.9        |  781.1        |  1053.2       |   837.6       | 0.8838731     | 0.4143224457  |\n",
       "| 13 | AB000466_at   |  254.8        |  230.1        |   265.6       |   315.6       |   308.6       |   239.0       |    80.1       |   268.1       |   213.8       | ...           |   334.6       |   275.6       |  271.8        |  195.3        |  216.1        |  191.3        |   240.2       |   159.4       | 1.1589296     | 0.3121915014  |\n",
       "| 14 | AB000467_at   | 1288.8        |  553.8        |   584.8       |  1551.2       |   454.8       |   410.9       |   151.2       |   240.4       |   619.2       | ...           |   310.8       |  1481.5       |  446.8        |  307.1        |  960.1        |  780.4        |   832.5       |   876.9       | 1.1346905     | 0.6098408798  |\n",
       "| 15 | AB000468_at   | 3932.7        | 4113.8        |  2913.4       |  1834.4       |  2080.5       |  1781.4       |  2054.2       |  1723.9       |  4117.3       | ...           |  3038.2       |  2897.3       | 5860.3        | 4784.3        | 5491.2        | 4909.5        |  6752.8       |  3183.8       | 1.2437960     | 0.0310017799  |\n",
       "| 16 | AB000584_at   | 7942.2        | 4851.0        |  3734.1       |  1611.0       |  4057.0       |  4433.8       |  4973.0       |  3974.1       |  6383.5       | ...           | 13762.8       |  8570.5       | 5096.6        | 6466.6        | 9896.3        | 8374.3        |  5511.4       |  3862.5       | 2.3576472     | 0.0006943714  |\n",
       "| 17 | AB000816_s_at |   63.4        |  126.0        |   116.9       |   648.8       |   832.8       |   507.5       |    58.5       |   284.6       |    61.0       | ...           |    55.9       |    94.2       |   43.6        |   31.0        |  343.8        |  231.1        |    37.4       |    34.2       | 0.7053565     | 0.4156251513  |\n",
       "| 18 | AB000895_at   |  366.9        |  349.2        |  1149.2       |  1196.6       |  1510.6       |   720.6       |   913.0       |   737.9       |   302.5       | ...           |   416.4       |   361.7       |  293.4        |  234.3        |  300.1        |  310.0        |   414.7       |   341.8       | 1.4204591     | 0.3442482565  |\n",
       "| 19 | AB000896_at   |  454.7        | 1305.2        |   562.5       |   145.4       |   219.0       |   981.7       |    62.9       |   619.6       |   806.6       | ...           |   776.6       |  1052.5       | 1213.5        | 1508.2        |  629.4        |  789.9        |   844.2       |   748.2       | 1.1998046     | 0.3262187657  |\n",
       "| 20 | AB000897_at   |  404.3        |  558.1        |   251.3       |   244.7       |  1037.2       |  1218.1       |    60.6       |    46.6       |   333.6       | ...           |   534.4       |   983.3       |  480.4        |  531.6        |  469.1        |  480.3        |   297.9       |   337.6       | 1.0579385     | 0.7740405906  |\n",
       "| 21 | AB000905_at   |  566.5        | 1470.4        |  1132.1       |   878.7       |   817.2       |  1379.8       |   368.4       |   544.6       |   520.8       | ...           |   577.5       |   958.4       |  510.4        |  615.6        |  402.4        |  339.9        |   555.4       |   327.4       | 1.0735278     | 0.6548151800  |\n",
       "| 22 | AB001106_at   | 1530.4        | 1178.6        |   646.8       |  1290.6       |  1550.7       |  2109.9       |   595.2       |   773.0       |  1238.4       | ...           |   908.6       |  1353.3       | 3184.3        | 2289.7        | 1688.3        | 1215.0        |  1325.8       |  1335.9       | 1.2692945     | 0.1738027968  |\n",
       "| 23 | AB001325_at   | 6114.8        | 6701.1        | 11676.8       | 12286.2       | 12672.5       | 11541.0       | 11897.8       | 12909.1       | 14098.0       | ...           | 15569.9       | 11471.7       | 8775.9        | 9434.1        | 8223.2        | 9480.4        | 17472.5       | 12793.5       | 1.0653241     | 0.5169829631  |\n",
       "| 24 | AB002314_at   |  317.3        |  590.9        |   823.1       |   283.0       |  1986.6       |  2046.1       |   963.9       |   893.8       |   486.7       | ...           |   576.9       |    89.4       | 1119.4        |  620.6        |  214.1        |  259.1        |   424.3       |   310.0       | 1.1020200     | 0.7194674566  |\n",
       "| 25 | AB002315_at   | 1654.6        | 2384.4        |  1077.1       |  2013.0       |  1117.1       |  1226.4       |  1100.1       |  1235.1       |  1617.5       | ...           |  1237.7       |  1561.7       | 2047.0        | 2268.5        | 2293.2        | 1715.0        |  1097.4       |  1447.1       | 1.0184359     | 0.8386048618  |\n",
       "| 26 | AB002318_at   | 3164.3        | 3521.6        |  3382.2       |  5517.7       |  2271.8       |  3149.1       |   339.2       |  1545.2       |  1944.0       | ...           |  2649.4       |  4960.5       | 2138.6        | 5906.9        | 2616.0        | 2671.8        |  3894.1       |  3076.9       | 1.0326219     | 0.7861666325  |\n",
       "| 27 | AB002332_at   | 1732.4        | 1659.3        |   928.0       |  1086.1       |  1210.9       |  1815.3       |  1394.1       |   989.8       |  1602.7       | ...           |  2569.6       |  2991.8       | 4468.7        | 4797.7        | 3222.2        | 2091.1        |  1889.9       |  2971.7       | 1.3542307     | 0.0137440249  |\n",
       "| 28 | AB002356_s_at | 2842.2        | 3210.0        |  5700.3       |  4649.6       |  5350.6       |  4210.5       |  4373.0       |  3833.6       |  4196.9       | ...           |  3416.1       |  4840.1       | 2861.1        | 2586.3        | 3531.6        | 3932.3        |  4509.2       |  4595.1       | 0.9552646     | 0.4455168414  |\n",
       "| 29 | AB002365_at   | 7780.9        | 5794.6        |   984.7       |   770.9       |   751.4       |   765.4       |  1848.7       |  1452.4       |  3304.0       | ...           |  5242.5       |  4063.0       | 9375.0        | 9765.9        | 8648.1        | 5156.5        |  3303.9       |  3450.7       | 1.4099952     | 0.0916796529  |\n",
       "| 30 | AB002366_at   |  228.8        |  616.2        |   628.2       |   709.0       |   368.2       |    60.1       |    19.5       |    19.1       |   304.7       | ...           |   197.0       |   136.5       |  698.1        |  171.5        |  261.3        |  286.8        |   220.5       |   232.6       | 0.7162988     | 0.1108929978  |\n",
       "| ... | ... | ... | ... | ... | ... | ... | ... | ... | ... | ... |     | ... | ... | ... | ... | ... | ... | ... | ... | ... | ... |\n",
       "| 7101 | Z80787_at                |   126.1                  |   497.5                  |     77.8                 |   1155.6                 |   576.1                  |   658.0                  |   395.0                  |   595.5                  |   299.9                  | ...                      |    66.6                  |   749.9                  |   166.6                  |   238.4                  |   110.9                  |    90.9                  |   219.9                  |   202.0                  | 0.8234044                | 0.43450344               |\n",
       "| 7102 | Z80788_at                |    73.9                  |   558.7                  |    102.3                 |    157.9                 |   193.7                  |   540.4                  |    37.0                  |   163.8                  |    42.7                  | ...                      |    45.2                  |   251.5                  |    53.6                  |    28.3                  |    35.1                  |   151.3                  |   338.2                  |    54.0                  | 0.8751380                | 0.65234488               |\n",
       "| 7103 | Z81326_at                |   788.8                  |   861.4                  |    179.4                 |    149.9                 |   156.9                  |   232.7                  |    78.8                  |   102.4                  |   447.5                  | ...                      |    89.9                  |    46.8                  |   324.8                  |   387.7                  |   278.7                  |   274.6                  |   260.7                  |    81.8                  | 1.0352864                | 0.87635058               |\n",
       "| 7104 | Z83336_at                |  2561.8                  |  4267.8                  |   2362.6                 |   2982.7                 |  3862.9                  |  3862.2                  |  2002.4                  |  2018.0                  |  1642.2                  | ...                      |  2995.4                  |  3604.4                  |  2077.6                  |  2937.8                  |  1633.8                  |  1275.1                  |  2200.8                  |  2032.8                  | 1.0149418                | 0.90149611               |\n",
       "| 7105 | Z83735_at                |    42.5                  |   269.2                  |    110.2                 |     53.9                 |   407.1                  |   116.2                  |    26.1                  |    14.8                  |    19.9                  | ...                      |    24.6                  |    54.1                  |    40.3                  |    16.0                  |    26.8                  |    37.9                  |    32.8                  |    28.7                  | 0.5469664                | 0.19080285               |\n",
       "| 7106 | Z83741_at                |   124.0                  |   131.1                  |    120.0                 |    179.8                 |   132.8                  |   173.3                  |    86.6                  |   125.5                  |   386.3                  | ...                      |   342.9                  |   406.5                  |    95.3                  |    81.0                  |    66.7                  |    64.1                  |   136.8                  |    90.8                  | 1.0860295                | 0.72942603               |\n",
       "| 7107 | Z83742_at                |    32.3                  |   165.7                  |    349.6                 |     53.9                 |   183.6                  |   572.5                  |    43.4                  |    31.6                  |    31.1                  | ...                      |    32.8                  |    65.5                  |    42.0                  |    23.1                  |    12.1                  |    23.6                  |    15.3                  |    25.4                  | 1.3071643                | 0.54474171               |\n",
       "| 7108 | Z83745_at                |   369.7                  |   726.4                  |   1343.1                 |    816.6                 |    90.7                  |   159.7                  |   148.6                  |    79.3                  |   243.1                  | ...                      |   118.9                  |   114.5                  |    48.8                  |    90.4                  |    55.6                  |    83.3                  |    55.1                  |   240.9                  | 0.5734646                | 0.13331411               |\n",
       "| 7109 | Z83799_at                |    26.1                  |    65.6                  |   1202.5                 |    286.2                 |   303.0                  |   321.9                  |    37.3                  |   162.6                  |    36.1                  | ...                      |    48.6                  |    54.5                  |    13.2                  |    17.7                  |    20.5                  |    33.7                  |    35.9                  |    32.1                  | 0.3939741                | 0.17242262               |\n",
       "| 7110 | Z83800_at                |   352.3                  |    19.4                  |    401.3                 |    576.2                 |   797.7                  |    64.6                  |    49.1                  |    40.7                  |   236.8                  | ...                      |    79.0                  |   143.8                  |   266.4                  |    15.0                  |   340.0                  |   154.4                  |   404.1                  |   294.7                  | 0.7905389                | 0.40226117               |\n",
       "| 7111 | Z83802_at                |   337.1                  |   307.2                  |    485.8                 |    678.4                 |  1076.9                  |   474.4                  |    56.9                  |   434.4                  |   283.2                  | ...                      |   582.9                  |   275.3                  |   326.8                  |   111.0                  |   543.6                  |   371.6                  |   588.8                  |   406.8                  | 0.8005771                | 0.26274790               |\n",
       "| 7112 | Z83803_at                |    68.5                  |    85.6                  |    116.8                 |    201.7                 |   165.7                  |   154.3                  |    51.7                  |   395.7                  |    68.9                  | ...                      |    76.4                  |    80.3                  |    44.4                  |    36.0                  |    41.1                  |    69.4                  |    68.1                  |    92.9                  | 0.6686448                | 0.07976404               |\n",
       "| 7113 | Z83804_at                |    61.3                  |    75.2                  |    729.2                 |    168.2                 |   683.2                  |   322.0                  |   237.4                  |   451.9                  |    81.3                  | ...                      |    91.3                  |   406.4                  |   148.3                  |   121.0                  |    71.9                  |   110.9                  |   244.2                  |   287.2                  | 0.7031139                | 0.20410284               |\n",
       "| 7114 | Z83805_at                |   179.6                  |   289.1                  |    284.0                 |    161.8                 |   145.0                  |   528.1                  |   116.4                  |   211.7                  |   525.8                  | ...                      |   943.5                  |   646.4                  |   158.0                  |   119.3                  |   577.8                  |   359.5                  |   893.2                  |   156.0                  | 1.2699898                | 0.35369954               |\n",
       "| 7115 | Z83806_at                |    53.5                  |    40.0                  |     87.1                 |    313.7                 |   177.0                  |   849.7                  |    32.8                  |   316.1                  |    52.0                  | ...                      |   213.8                  |    90.5                  |   104.9                  |     5.4                  |    16.3                  |    16.4                  |    22.5                  |    35.7                  | 0.4292699                | 0.09874292               |\n",
       "| 7116 | Z83821_cds2_at           |   146.1                  |   278.1                  |   2058.7                 |    249.6                 |   207.8                  |   394.5                  |   199.5                  |   344.1                  |   307.0                  | ...                      |   610.4                  |   382.9                  |  1118.7                  |  1178.8                  |   166.3                  |   670.9                  |   252.9                  |   253.7                  | 0.7882485                | 0.43623384               |\n",
       "| 7117 | Z84483_at                |   185.9                  |   256.8                  |    478.2                 |   2029.4                 |   307.5                  |   742.8                  |    63.9                  |   361.6                  |   239.0                  | ...                      |   495.8                  |   173.2                  |   148.9                  |   312.4                  |   292.7                  |   410.9                  |   392.9                  |   421.4                  | 0.7476435                | 0.29435917               |\n",
       "| 7118 | Z84497_s_at              |  1125.0                  |   853.0                  |   2876.2                 |   3792.7                 |  2349.3                  |  2008.5                  |  3001.0                  |  3842.2                  |  3214.9                  | ...                      |  2308.3                  |  2161.1                  |  1872.1                  |  1185.6                  |  3422.3                  |  3197.5                  |  3283.9                  |  3006.6                  | 0.9001073                | 0.28281687               |\n",
       "| 7119 | Z84718_cds1_at           |  2431.2                  |  1020.5                  |   1098.8                 |    968.2                 |  3332.0                  |  1502.9                  |  4954.9                  |   362.4                  |   171.6                  | ...                      |  4677.9                  |  3882.0                  |  2561.0                  |  2550.5                  |  2872.5                  |  2619.0                  |   151.6                  |   131.0                  | 1.6946233                | 0.02026355               |\n",
       "| 7120 | Z84721_cds1_at           |   535.7                  |  1481.3                  |   1838.9                 |   2931.4                 |   325.4                  |  1757.0                  |  2157.3                  |   403.3                  |   916.9                  | ...                      |  2566.6                  |  1672.5                  |   312.5                  |  1611.4                  |   307.4                  |   831.7                  |   933.2                  |  1145.8                  | 1.0160060                | 0.92983366               |\n",
       "| 7121 | Z84721_cds2_at           | 23432.4                  | 41449.0                  | 159758.0                 | 177615.7                 | 19759.5                  | 24325.3                  | 23243.7                  | 25641.3                  | 80800.6                  | ...                      | 14150.8                  | 27130.8                  | 85301.5                  | 76879.9                  | 30098.0                  | 27347.9                  | 10624.8                  | 16387.8                  | 0.5790154                | 0.04061564               |\n",
       "| 7122 | Z84722_at                |   366.7                  |   420.2                  |    312.9                 |    522.4                 |   485.6                  |   262.0                  |   168.9                  |   939.8                  |   379.1                  | ...                      |   204.8                  |   457.0                  |   202.6                  |   144.5                  |   182.3                  |   182.6                  |   230.8                  |   235.7                  | 0.8447253                | 0.29572328               |\n",
       "| 7123 | Z86000_at                |  1202.6                  |  2693.6                  |   2538.3                 |   1623.5                 |  2700.2                  |  2929.6                  |  1896.8                  |  1482.5                  |  1729.3                  | ...                      |  1419.2                  |  2507.1                  |  1372.8                  |  1759.6                  |  1282.1                  |  1636.9                  |  2858.3                  |  2130.6                  | 0.9233079                | 0.45124679               |\n",
       "| 7124 | Z93784_at                |  2439.4                  |  2272.7                  |   3203.0                 |   2803.5                 |  4800.7                  |  2997.4                  |  2089.7                  |  2251.9                  |  3487.3                  | ...                      |  2748.0                  |  1570.0                  |  2403.3                  |  2482.0                  |  3044.4                  |  2692.3                  |  3655.4                  |  2798.9                  | 0.8241107                | 0.02385007               |\n",
       "| 7125 | Z94753_s_at              |   429.7                  |   911.7                  |   1171.2                 |    516.1                 |   737.9                  |  1157.7                  |   211.6                  |   522.2                  |   309.9                  | ...                      |   365.9                  |  1413.1                  |   558.3                  |   227.6                  |   775.7                  |   997.8                  |   331.3                  |   376.4                  | 1.1540683                | 0.42713655               |\n",
       "| 7126 | Z95624_at                |   351.9                  |   105.7                  |    946.4                 |    389.3                 |   238.1                  |  1216.7                  |   227.3                  |   207.1                  |   244.2                  | ...                      |   313.5                  |   300.7                  |   120.1                  |   293.7                  |   289.1                  |   291.6                  |   359.7                  |   367.3                  | 0.9463065                | 0.79422427               |\n",
       "| 7127 | Z96810_at                |   411.1                  |   532.0                  |   1382.2                 |    242.2                 |   247.2                  |   940.0                  |   458.3                  |   689.7                  |   760.6                  | ...                      |   515.5                  |   925.0                  |   380.7                  |   252.1                  |   443.5                  |   512.0                  |   753.9                  |   741.6                  | 0.7585332                | 0.06665884               |\n",
       "| 7128 | Z97054_xpt2_at           |  1598.2                  |  1059.8                  |   2133.0                 |   2847.0                 |  1369.1                  |  1783.8                  |  2786.8                  |  2616.4                  |  3217.6                  | ...                      |  2294.0                  |  2282.3                  |  2347.0                  |  2032.5                  |  3736.4                  |  3044.0                  |  2681.7                  |  3285.7                  | 1.0767952                | 0.35905502               |\n",
       "| 7129 | Z97074_at                |  1277.9                  |  1370.1                  |   2514.6                 |    277.4                 |  2461.0                  |  1248.9                  |  1726.4                  |  1260.2                  |  1085.5                  | ...                      |  1475.8                  |   737.4                  |  1614.7                  |  1421.4                  |  1238.9                  |  1719.9                  |   936.3                  |  1254.6                  | 0.9389230                | 0.57004284               |\n",
       "|  | !series_matrix_table_end |      NA                  |      NA                  |       NA                 |       NA                 |      NA                  |      NA                  |      NA                  |      NA                  |      NA                  | ...                      |      NA                  |      NA                  |      NA                  |      NA                  |      NA                  |      NA                  |      NA                  |      NA                  |        NA                |         NA               |\n",
       "\n"
      ],
      "text/plain": [
       "     ID_REF                   GSM114034 GSM114035 GSM114036 GSM114037 GSM114038\n",
       "1    A28102_at                 808.3    1390.2      927.4    2360.4    1811.4  \n",
       "2    AB000114_at               266.2     661.4      231.6      58.9     409.8  \n",
       "3    AB000115_at              1534.3    1657.5      176.2    1472.0    2263.2  \n",
       "4    AB000220_at              6734.1    4809.9      566.5    1777.2    1703.8  \n",
       "5    AB000381_s_at             213.5     119.6      179.2     189.3     301.5  \n",
       "6    AB000409_at              1259.6    2000.4      115.9     948.0     443.2  \n",
       "7    AB000410_s_at             196.2     226.8      416.3     611.0     257.3  \n",
       "8    AB000449_at               738.9     981.9      747.2     770.7     311.2  \n",
       "9    AB000450_at              1730.1    2172.4      634.9      92.9      93.7  \n",
       "10   AB000460_at              3226.0    4180.1     2324.8    4784.3    2248.0  \n",
       "11   AB000462_at               561.9     678.7       86.5    1143.4     884.8  \n",
       "12   AB000464_at              1789.1    1734.0      561.1    1051.8     774.5  \n",
       "13   AB000466_at               254.8     230.1      265.6     315.6     308.6  \n",
       "14   AB000467_at              1288.8     553.8      584.8    1551.2     454.8  \n",
       "15   AB000468_at              3932.7    4113.8     2913.4    1834.4    2080.5  \n",
       "16   AB000584_at              7942.2    4851.0     3734.1    1611.0    4057.0  \n",
       "17   AB000816_s_at              63.4     126.0      116.9     648.8     832.8  \n",
       "18   AB000895_at               366.9     349.2     1149.2    1196.6    1510.6  \n",
       "19   AB000896_at               454.7    1305.2      562.5     145.4     219.0  \n",
       "20   AB000897_at               404.3     558.1      251.3     244.7    1037.2  \n",
       "21   AB000905_at               566.5    1470.4     1132.1     878.7     817.2  \n",
       "22   AB001106_at              1530.4    1178.6      646.8    1290.6    1550.7  \n",
       "23   AB001325_at              6114.8    6701.1    11676.8   12286.2   12672.5  \n",
       "24   AB002314_at               317.3     590.9      823.1     283.0    1986.6  \n",
       "25   AB002315_at              1654.6    2384.4     1077.1    2013.0    1117.1  \n",
       "26   AB002318_at              3164.3    3521.6     3382.2    5517.7    2271.8  \n",
       "27   AB002332_at              1732.4    1659.3      928.0    1086.1    1210.9  \n",
       "28   AB002356_s_at            2842.2    3210.0     5700.3    4649.6    5350.6  \n",
       "29   AB002365_at              7780.9    5794.6      984.7     770.9     751.4  \n",
       "30   AB002366_at               228.8     616.2      628.2     709.0     368.2  \n",
       "...  ...                      ...       ...       ...       ...       ...      \n",
       "7101 Z80787_at                  126.1     497.5       77.8    1155.6    576.1  \n",
       "7102 Z80788_at                   73.9     558.7      102.3     157.9    193.7  \n",
       "7103 Z81326_at                  788.8     861.4      179.4     149.9    156.9  \n",
       "7104 Z83336_at                 2561.8    4267.8     2362.6    2982.7   3862.9  \n",
       "7105 Z83735_at                   42.5     269.2      110.2      53.9    407.1  \n",
       "7106 Z83741_at                  124.0     131.1      120.0     179.8    132.8  \n",
       "7107 Z83742_at                   32.3     165.7      349.6      53.9    183.6  \n",
       "7108 Z83745_at                  369.7     726.4     1343.1     816.6     90.7  \n",
       "7109 Z83799_at                   26.1      65.6     1202.5     286.2    303.0  \n",
       "7110 Z83800_at                  352.3      19.4      401.3     576.2    797.7  \n",
       "7111 Z83802_at                  337.1     307.2      485.8     678.4   1076.9  \n",
       "7112 Z83803_at                   68.5      85.6      116.8     201.7    165.7  \n",
       "7113 Z83804_at                   61.3      75.2      729.2     168.2    683.2  \n",
       "7114 Z83805_at                  179.6     289.1      284.0     161.8    145.0  \n",
       "7115 Z83806_at                   53.5      40.0       87.1     313.7    177.0  \n",
       "7116 Z83821_cds2_at             146.1     278.1     2058.7     249.6    207.8  \n",
       "7117 Z84483_at                  185.9     256.8      478.2    2029.4    307.5  \n",
       "7118 Z84497_s_at               1125.0     853.0     2876.2    3792.7   2349.3  \n",
       "7119 Z84718_cds1_at            2431.2    1020.5     1098.8     968.2   3332.0  \n",
       "7120 Z84721_cds1_at             535.7    1481.3     1838.9    2931.4    325.4  \n",
       "7121 Z84721_cds2_at           23432.4   41449.0   159758.0  177615.7  19759.5  \n",
       "7122 Z84722_at                  366.7     420.2      312.9     522.4    485.6  \n",
       "7123 Z86000_at                 1202.6    2693.6     2538.3    1623.5   2700.2  \n",
       "7124 Z93784_at                 2439.4    2272.7     3203.0    2803.5   4800.7  \n",
       "7125 Z94753_s_at                429.7     911.7     1171.2     516.1    737.9  \n",
       "7126 Z95624_at                  351.9     105.7      946.4     389.3    238.1  \n",
       "7127 Z96810_at                  411.1     532.0     1382.2     242.2    247.2  \n",
       "7128 Z97054_xpt2_at            1598.2    1059.8     2133.0    2847.0   1369.1  \n",
       "7129 Z97074_at                 1277.9    1370.1     2514.6     277.4   2461.0  \n",
       "     !series_matrix_table_end      NA        NA         NA        NA       NA  \n",
       "     GSM114039 GSM114040 GSM114041 GSM114042 ... GSM114070 GSM114071 GSM114072\n",
       "1     1622.7     687.9    1686.7     725.6   ...   860.1    1516.6    827.6   \n",
       "2     1420.4     474.1     313.2     416.7   ...   401.3     511.3    451.1   \n",
       "3     1824.5    3256.6     342.2     715.4   ...   431.4    1188.5   1001.8   \n",
       "4     1873.8    3349.6     506.7    3789.4   ...  1767.3    3274.8   6808.7   \n",
       "5      394.2     104.5     164.8     258.0   ...   214.6      19.7    147.9   \n",
       "6     1340.9    2002.3     711.9    1727.9   ...  1649.8    2041.7   2216.3   \n",
       "7      457.3     232.0     311.2     254.2   ...   275.7     178.3    155.9   \n",
       "8     1031.8     273.3     568.3     923.5   ...   680.9     900.6   1163.6   \n",
       "9     1494.6     318.5     163.4    1148.2   ...  1345.3    1434.2   1388.6   \n",
       "10    2046.0    2212.9    1978.4    4025.7   ...  3830.3    4688.5   4178.1   \n",
       "11     613.4     258.3     733.6    1261.0   ...   877.1    1117.1    648.6   \n",
       "12    1755.2     676.1    1012.5    1920.5   ...  1297.6    1897.0   1075.1   \n",
       "13     239.0      80.1     268.1     213.8   ...   334.6     275.6    271.8   \n",
       "14     410.9     151.2     240.4     619.2   ...   310.8    1481.5    446.8   \n",
       "15    1781.4    2054.2    1723.9    4117.3   ...  3038.2    2897.3   5860.3   \n",
       "16    4433.8    4973.0    3974.1    6383.5   ... 13762.8    8570.5   5096.6   \n",
       "17     507.5      58.5     284.6      61.0   ...    55.9      94.2     43.6   \n",
       "18     720.6     913.0     737.9     302.5   ...   416.4     361.7    293.4   \n",
       "19     981.7      62.9     619.6     806.6   ...   776.6    1052.5   1213.5   \n",
       "20    1218.1      60.6      46.6     333.6   ...   534.4     983.3    480.4   \n",
       "21    1379.8     368.4     544.6     520.8   ...   577.5     958.4    510.4   \n",
       "22    2109.9     595.2     773.0    1238.4   ...   908.6    1353.3   3184.3   \n",
       "23   11541.0   11897.8   12909.1   14098.0   ... 15569.9   11471.7   8775.9   \n",
       "24    2046.1     963.9     893.8     486.7   ...   576.9      89.4   1119.4   \n",
       "25    1226.4    1100.1    1235.1    1617.5   ...  1237.7    1561.7   2047.0   \n",
       "26    3149.1     339.2    1545.2    1944.0   ...  2649.4    4960.5   2138.6   \n",
       "27    1815.3    1394.1     989.8    1602.7   ...  2569.6    2991.8   4468.7   \n",
       "28    4210.5    4373.0    3833.6    4196.9   ...  3416.1    4840.1   2861.1   \n",
       "29     765.4    1848.7    1452.4    3304.0   ...  5242.5    4063.0   9375.0   \n",
       "30      60.1      19.5      19.1     304.7   ...   197.0     136.5    698.1   \n",
       "...  ...       ...       ...       ...           ...       ...       ...      \n",
       "7101   658.0     395.0     595.5     299.9   ...    66.6     749.9     166.6  \n",
       "7102   540.4      37.0     163.8      42.7   ...    45.2     251.5      53.6  \n",
       "7103   232.7      78.8     102.4     447.5   ...    89.9      46.8     324.8  \n",
       "7104  3862.2    2002.4    2018.0    1642.2   ...  2995.4    3604.4    2077.6  \n",
       "7105   116.2      26.1      14.8      19.9   ...    24.6      54.1      40.3  \n",
       "7106   173.3      86.6     125.5     386.3   ...   342.9     406.5      95.3  \n",
       "7107   572.5      43.4      31.6      31.1   ...    32.8      65.5      42.0  \n",
       "7108   159.7     148.6      79.3     243.1   ...   118.9     114.5      48.8  \n",
       "7109   321.9      37.3     162.6      36.1   ...    48.6      54.5      13.2  \n",
       "7110    64.6      49.1      40.7     236.8   ...    79.0     143.8     266.4  \n",
       "7111   474.4      56.9     434.4     283.2   ...   582.9     275.3     326.8  \n",
       "7112   154.3      51.7     395.7      68.9   ...    76.4      80.3      44.4  \n",
       "7113   322.0     237.4     451.9      81.3   ...    91.3     406.4     148.3  \n",
       "7114   528.1     116.4     211.7     525.8   ...   943.5     646.4     158.0  \n",
       "7115   849.7      32.8     316.1      52.0   ...   213.8      90.5     104.9  \n",
       "7116   394.5     199.5     344.1     307.0   ...   610.4     382.9    1118.7  \n",
       "7117   742.8      63.9     361.6     239.0   ...   495.8     173.2     148.9  \n",
       "7118  2008.5    3001.0    3842.2    3214.9   ...  2308.3    2161.1    1872.1  \n",
       "7119  1502.9    4954.9     362.4     171.6   ...  4677.9    3882.0    2561.0  \n",
       "7120  1757.0    2157.3     403.3     916.9   ...  2566.6    1672.5     312.5  \n",
       "7121 24325.3   23243.7   25641.3   80800.6   ... 14150.8   27130.8   85301.5  \n",
       "7122   262.0     168.9     939.8     379.1   ...   204.8     457.0     202.6  \n",
       "7123  2929.6    1896.8    1482.5    1729.3   ...  1419.2    2507.1    1372.8  \n",
       "7124  2997.4    2089.7    2251.9    3487.3   ...  2748.0    1570.0    2403.3  \n",
       "7125  1157.7     211.6     522.2     309.9   ...   365.9    1413.1     558.3  \n",
       "7126  1216.7     227.3     207.1     244.2   ...   313.5     300.7     120.1  \n",
       "7127   940.0     458.3     689.7     760.6   ...   515.5     925.0     380.7  \n",
       "7128  1783.8    2786.8    2616.4    3217.6   ...  2294.0    2282.3    2347.0  \n",
       "7129  1248.9    1726.4    1260.2    1085.5   ...  1475.8     737.4    1614.7  \n",
       "          NA        NA        NA        NA   ...      NA        NA        NA  \n",
       "     GSM114073 GSM114074 GSM114075 GSM114076 GSM114077 fold_change p_value     \n",
       "1     955.0     731.0     601.8      736.2     534.5   1.2205307   0.4646315973\n",
       "2     266.8     281.6     259.2      237.7     184.4   1.6738898   0.2057826183\n",
       "3     654.3     915.0     585.0      783.9     981.9   1.1665101   0.6462842946\n",
       "4    4181.7    4481.5    3384.0     3779.8    4480.1   1.1164064   0.4837524591\n",
       "5      36.2      37.2     104.6      164.8     139.3   0.7910773   0.3202725473\n",
       "6    2283.3    2462.3    2096.5     1881.8    1788.7   1.2924453   0.1561640071\n",
       "7     134.3     143.2     177.0      252.2     246.6   0.7104267   0.0662604682\n",
       "8     600.0     527.4     415.5      404.6     335.1   1.4421654   0.2666760439\n",
       "9    1714.9    1430.8     946.6     1124.3     758.3   1.2933856   0.1630920683\n",
       "10   4736.3    4023.0    3375.1     4664.3    3401.1   1.0223681   0.7990893435\n",
       "11    866.5     574.5     513.2      436.3     483.1   0.8549584   0.4080222344\n",
       "12    979.9     959.9     781.1     1053.2     837.6   0.8838731   0.4143224457\n",
       "13    195.3     216.1     191.3      240.2     159.4   1.1589296   0.3121915014\n",
       "14    307.1     960.1     780.4      832.5     876.9   1.1346905   0.6098408798\n",
       "15   4784.3    5491.2    4909.5     6752.8    3183.8   1.2437960   0.0310017799\n",
       "16   6466.6    9896.3    8374.3     5511.4    3862.5   2.3576472   0.0006943714\n",
       "17     31.0     343.8     231.1       37.4      34.2   0.7053565   0.4156251513\n",
       "18    234.3     300.1     310.0      414.7     341.8   1.4204591   0.3442482565\n",
       "19   1508.2     629.4     789.9      844.2     748.2   1.1998046   0.3262187657\n",
       "20    531.6     469.1     480.3      297.9     337.6   1.0579385   0.7740405906\n",
       "21    615.6     402.4     339.9      555.4     327.4   1.0735278   0.6548151800\n",
       "22   2289.7    1688.3    1215.0     1325.8    1335.9   1.2692945   0.1738027968\n",
       "23   9434.1    8223.2    9480.4    17472.5   12793.5   1.0653241   0.5169829631\n",
       "24    620.6     214.1     259.1      424.3     310.0   1.1020200   0.7194674566\n",
       "25   2268.5    2293.2    1715.0     1097.4    1447.1   1.0184359   0.8386048618\n",
       "26   5906.9    2616.0    2671.8     3894.1    3076.9   1.0326219   0.7861666325\n",
       "27   4797.7    3222.2    2091.1     1889.9    2971.7   1.3542307   0.0137440249\n",
       "28   2586.3    3531.6    3932.3     4509.2    4595.1   0.9552646   0.4455168414\n",
       "29   9765.9    8648.1    5156.5     3303.9    3450.7   1.4099952   0.0916796529\n",
       "30    171.5     261.3     286.8      220.5     232.6   0.7162988   0.1108929978\n",
       "...  ...       ...       ...       ...       ...       ...         ...         \n",
       "7101   238.4     110.9      90.9     219.9     202.0   0.8234044   0.43450344  \n",
       "7102    28.3      35.1     151.3     338.2      54.0   0.8751380   0.65234488  \n",
       "7103   387.7     278.7     274.6     260.7      81.8   1.0352864   0.87635058  \n",
       "7104  2937.8    1633.8    1275.1    2200.8    2032.8   1.0149418   0.90149611  \n",
       "7105    16.0      26.8      37.9      32.8      28.7   0.5469664   0.19080285  \n",
       "7106    81.0      66.7      64.1     136.8      90.8   1.0860295   0.72942603  \n",
       "7107    23.1      12.1      23.6      15.3      25.4   1.3071643   0.54474171  \n",
       "7108    90.4      55.6      83.3      55.1     240.9   0.5734646   0.13331411  \n",
       "7109    17.7      20.5      33.7      35.9      32.1   0.3939741   0.17242262  \n",
       "7110    15.0     340.0     154.4     404.1     294.7   0.7905389   0.40226117  \n",
       "7111   111.0     543.6     371.6     588.8     406.8   0.8005771   0.26274790  \n",
       "7112    36.0      41.1      69.4      68.1      92.9   0.6686448   0.07976404  \n",
       "7113   121.0      71.9     110.9     244.2     287.2   0.7031139   0.20410284  \n",
       "7114   119.3     577.8     359.5     893.2     156.0   1.2699898   0.35369954  \n",
       "7115     5.4      16.3      16.4      22.5      35.7   0.4292699   0.09874292  \n",
       "7116  1178.8     166.3     670.9     252.9     253.7   0.7882485   0.43623384  \n",
       "7117   312.4     292.7     410.9     392.9     421.4   0.7476435   0.29435917  \n",
       "7118  1185.6    3422.3    3197.5    3283.9    3006.6   0.9001073   0.28281687  \n",
       "7119  2550.5    2872.5    2619.0     151.6     131.0   1.6946233   0.02026355  \n",
       "7120  1611.4     307.4     831.7     933.2    1145.8   1.0160060   0.92983366  \n",
       "7121 76879.9   30098.0   27347.9   10624.8   16387.8   0.5790154   0.04061564  \n",
       "7122   144.5     182.3     182.6     230.8     235.7   0.8447253   0.29572328  \n",
       "7123  1759.6    1282.1    1636.9    2858.3    2130.6   0.9233079   0.45124679  \n",
       "7124  2482.0    3044.4    2692.3    3655.4    2798.9   0.8241107   0.02385007  \n",
       "7125   227.6     775.7     997.8     331.3     376.4   1.1540683   0.42713655  \n",
       "7126   293.7     289.1     291.6     359.7     367.3   0.9463065   0.79422427  \n",
       "7127   252.1     443.5     512.0     753.9     741.6   0.7585332   0.06665884  \n",
       "7128  2032.5    3736.4    3044.0    2681.7    3285.7   1.0767952   0.35905502  \n",
       "7129  1421.4    1238.9    1719.9     936.3    1254.6   0.9389230   0.57004284  \n",
       "          NA        NA        NA        NA        NA          NA           NA  "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "dfrm_2"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# 0515 Continue Works\n",
    "## Requirement\n",
    "1. 非差异表达 空心\n",
    "2. 差异表达 非空心\n",
    "3. 3条辅助线 （2p,1f）\n"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "metadata": {
    "scrolled": false
   },
   "outputs": [
    {
     "data": {
      "image/png": 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A0wFSl7wCXjXh1Ij6lr/ycE/Ui1QKR2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",
      "text/plain": [
       "Plot with title \"Volcano Plot of GSE5056\""
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# Plot()\n",
    "#pdf(\"Volcano_Plot_of_GSE5056_zzf_0515.pdf\")\n",
    "# Prepare for the Basic plot\n",
    "plot(log2(dfrm_2$fold_change), -log10(dfrm_2$p_value), type='n', main=\"Volcano Plot of GSE5056\",xlab=\"log2(fold_change)\", ylab=\"-log10(p_value)\")\n",
    "grid()\n",
    "# Set the Cutoff\n",
    "co_p <- 2 # cutoff of p_value: 0.01 (-log10(0.01) = 2)\n",
    "co_f <- 0.35 # cutoff of fold_change: +-1.274561(log2(cutoff) = +-0.35)\n",
    "col_p <- rgb(0,206,209,maxColorValue=255)\n",
    "# Get the SubSet data aaccording to the cutoff\n",
    "var <- subset(dfrm_2, (fold_change > 2^co_f | fold_change < 2^-co_f) & p_value < 10^-co_p) # differential expression\n",
    "nor <- subset(dfrm_2, (fold_change <= 2^co_f & fold_change >= 2^-co_f) | p_value >= 10^-co_p)\n",
    "# Plot the points of different SubSet\n",
    "points(log2(var$fold_change), -log10(var$p_value), col=col_p, pch = 19)\n",
    "points(log2(nor$fold_change), -log10(nor$p_value), col = rgb(0, 0, 0, 35, maxColorValue=255))\n",
    "# plot the lines of cutoff using abline()\n",
    "abline(h=co_p, col=rgb(176,196,222,maxColorValue=255), lty=2)\n",
    "abline(v=co_f, col=rgb(0,139,139,maxColorValue=255), lty=2)\n",
    "abline(v=-co_f, col=rgb(0,139,139,maxColorValue=255), lty=2)\n",
    "# Add the legend\n",
    "legend(\"topleft\", pch=c(19,1), , col=c(col_p,rgb(0,0,0)), legend=c('Differential expression','Normal expression'))\n",
    "\n",
    "#dev.off()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "R",
   "language": "R",
   "name": "ir"
  },
  "language_info": {
   "codemirror_mode": "r",
   "file_extension": ".r",
   "mimetype": "text/x-r-source",
   "name": "R",
   "pygments_lexer": "r",
   "version": "3.5.1"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 2
}
